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    CG10298 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 40779, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG10298provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0037432
    Locus tag
    Dmel_CG10298
    See related
    AllianceGenome:FB:FBgn0037432
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BcDNA:GH28351; Dmel\CG10298
    Summary
    Predicted to be involved in negative regulation of ERK1 and ERK2 cascade. Predicted to be located in cytosol. Is expressed in testis. Human ortholog(s) of this gene implicated in prostate cancer. Orthologous to human PEBP1 (phosphatidylethanolamine binding protein 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG10298 in Genome Data Viewer
    Location:
    83E4-83E4; 3-47.5 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (6343002..6343799)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (2168724..2169521)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene Osiris 20 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Small ribonucleoprotein particle protein SmD2 Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Expression and characterization of the PEBP homolog genes from Drosophila. Rautureau G, et al. Arch Insect Biochem Physiol, 2009 Jun. PMID 19309003
    2. The tobacco phosphatidylethanolamine-binding protein NtFT4 increases the lifespan of Drosophila melanogaster by interacting with the proteostasis network. Känel P, et al. Aging (Albany NY), 2022 Apr 8. PMID 35396341, Free PMC Article
    3. Identification of GOLPH3 Partners in Drosophila Unveils Potential Novel Roles in Tumorigenesis and Neural Disorders. Sechi S, et al. Cells, 2021 Sep 6. PMID 34571985, Free PMC Article
    4. mRNA-Associated Processes and Their Influence on Exon-Intron Structure in Drosophila melanogaster. Lepennetier G, et al. G3 (Bethesda), 2016 Jun 1. PMID 27172210, Free PMC Article
    5. CRISPR-based modular assembly of a UAS-cDNA/ORF plasmid library for more than 5500 Drosophila genes conserved in humans. Wei P, et al. Genome Res, 2020 Jan. PMID 31722958, Free PMC Article

    See all (25) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in negative regulation of ERK1 and ERK2 cascade ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytosol ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG10298-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      6343002..6343799
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_141386.2 → NP_649643.1  uncharacterized protein Dmel_CG10298 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_649643.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VI08
      Related
      FBpp0081207
      Conserved Domains (1) summary
      cd00866
      Location:24 → 170
      PEBP_euk; PhosphatidylEthanolamine-Binding Protein (PEBP) domain present in eukaryotes
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VI08 Q9VI08

    Gene LinkOut

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