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    Cyp304a1 Cytochrome P450 304a1 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 41586, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Cyp304a1provided by FlyBase
    Official Full Name
    Cytochrome P450 304a1provided by FlyBase
    Primary source
    FLYBASE:FBgn0038095
    Locus tag
    Dmel_CG7241
    See related
    AllianceGenome:FB:FBgn0038095
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    304a1; BcDNA:LP06355; CG7241; Cyp304A1; CYP304a1; CYP304A1; CYP304A1-Dm; Dmel\CG7241
    Summary
    Predicted to enable several functions, including heme binding activity; iron ion binding activity; and monooxygenase activity. Is expressed in adult fat body; amnioserosa; embryonic/larval midgut; organism; and yolk nucleus. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Cyp304a1 in Genome Data Viewer
    Location:
    87D5-87D5; 3-53 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (12963791..12965923)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (8789513..8791645)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene beaten path Vb Neighboring gene long non-coding RNA:CR44236 Neighboring gene granny smith Neighboring gene Spc25 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The involvement of cytochrome P450 monooxygenases in methanol elimination in Drosophila melanogaster larvae. Wang SP, et al. Arch Insect Biochem Physiol, 2012 Apr. PMID 22508581
    2. Association of detoxification enzymes with butene-fipronil in larvae and adults of Drosophila melanogaster. Arain MS, et al. Environ Sci Pollut Res Int, 2018 Apr. PMID 29380196
    3. Transcript level is a key factor affecting RNAi efficiency. Chen J, et al. Pestic Biochem Physiol, 2021 Jul. PMID 34119217
    4. The involvement of several enzymes in methanol detoxification in Drosophila melanogaster adults. Wang SP, et al. Comp Biochem Physiol B Biochem Mol Biol, 2013 Sep. PMID 23751173
    5. CYP306A1, a cytochrome P450 enzyme, is essential for ecdysteroid biosynthesis in the prothoracic glands of Bombyx and Drosophila. Niwa R, et al. J Biol Chem, 2004 Aug 20. PMID 15197185

    See all (47) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables heme binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables iron ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables monooxygenase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    cytochrome P450 304a1
    Names
    CG7241-PA
    Cyp304a1-PA
    cytochrome P450
    NP_731751.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      12963791..12965923
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_169484.2 → NP_731751.1  cytochrome P450 304a1 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_731751.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9VG17
      Related
      FBpp0082159
      Conserved Domains (1) summary
      pfam00067
      Location:30 → 504
      p450; Cytochrome P450
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VG17.2 Q9VG17

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Other Literature Sources
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