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    CG9997 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 43395, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG9997provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0039597
    Locus tag
    Dmel_CG9997
    See related
    AllianceGenome:FB:FBgn0039597
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG9997; SPH252
    Summary
    Involved in protein localization; regulation of female receptivity, post-mating; and sperm competition. Located in extracellular space. Is expressed in adult head. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG9997 in Genome Data Viewer
    Location:
    98E3-98E3; 3-97 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (28755484..28756979, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (24581206..24582701, complement)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene Allatostatin A receptor 2 Neighboring gene uncharacterized protein Neighboring gene aquarius Neighboring gene long non-coding RNA:CR46496

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A predominant role of genotypic variation in both expression of sperm competition genes and paternity success in Drosophila melanogaster. Patlar B, et al. Proc Biol Sci, 2023 Sep 27. PMID 37727083, Free PMC Article
    2. Intraspecific sperm competition genes enforce post-mating species barriers in Drosophila. Castillo DM, et al. Proc Biol Sci, 2014 Dec 22. PMID 25355478, Free PMC Article
    3. Male reproductive aging arises via multifaceted mating-dependent sperm and seminal proteome declines, but is postponable in Drosophila. Sepil I, et al. Proc Natl Acad Sci U S A, 2020 Jul 21. PMID 32611817, Free PMC Article
    4. Sex peptide is required for the efficient release of stored sperm in mated Drosophila females. Avila FW, et al. Genetics, 2010 Oct. PMID 20679516, Free PMC Article
    5. A network of interactions among seminal proteins underlies the long-term postmating response in Drosophila. Ram KR, et al. Proc Natl Acad Sci U S A, 2009 Sep 8. PMID 19706411, Free PMC Article

    See all (54) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    NOT enables peptidase activity IKR
    Inferred from Key Residues
    more info
    		  
    NOT enables serine-type endopeptidase activity IKR
    Inferred from Key Residues
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in protein localization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in regulation of female receptivity, post-mating IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in sexual reproduction HEP PubMed 
    involved_in sperm competition IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular space HDA PubMed 
    located_in extracellular space ISM
    Inferred from Sequence Model
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG9997-PA
    CG9997-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      28755484..28756979 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001276114.1 → NP_001263043.1  uncharacterized protein Dmel_CG9997, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001263043.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      B1P7F6, Q4V686, Q9VAT8
      Conserved Domains (1) summary
      pfam00089
      Location:120 → 312
      Trypsin; Trypsin

    2. NM_143374.2 → NP_651631.1  uncharacterized protein Dmel_CG9997, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_651631.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      B1P7F6, Q4V686, Q9VAT8
      Related
      FBpp0084683
      Conserved Domains (1) summary
      pfam00089
      Location:120 → 312
      Trypsin; Trypsin
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VAT8 Q9VAT8

    Gene LinkOut

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