U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    aqrs aquarius [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 43396, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    aqrsprovided by FlyBase
    Official Full Name
    aquariusprovided by FlyBase
    Primary source
    FLYBASE:FBgn0039598
    Locus tag
    Dmel_CG14061
    See related
    AllianceGenome:FB:FBgn0039598
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Aqrs; CG14061; Dmel\CG14061; SPH255
    Summary
    Involved in negative regulation of female receptivity, post-mating and sperm storage. Located in extracellular space. Is expressed in adult head. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See aqrs in Genome Data Viewer
    Location:
    98E3-98E3; 3-97 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (28756999..28758234, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (24582721..24583956, complement)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR46496 Neighboring gene long non-coding RNA:CR46497

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Long-term interaction between Drosophila sperm and sex peptide is mediated by other seminal proteins that bind only transiently to sperm. Singh A, et al. Insect Biochem Mol Biol, 2018 Nov. PMID 30217614, Free PMC Article
    2. Divergent allocation of sperm and the seminal proteome along a competition gradient in Drosophila melanogaster. Hopkins BR, et al. Proc Natl Acad Sci U S A, 2019 Sep 3. PMID 31431535, Free PMC Article
    3. The life history of Drosophila sperm involves molecular continuity between male and female reproductive tracts. McCullough EL, et al. Proc Natl Acad Sci U S A, 2022 Mar 15. PMID 35254899, Free PMC Article
    4. Molecular evolution of the sex peptide network in Drosophila. McGeary MK, et al. J Evol Biol, 2020 May. PMID 31991034
    5. The evolution of seminal fluid gene expression and postmating reproductive isolation in Drosophila. Flacchi C, et al. Evolution, 2024 May 1. PMID 38416119

    See all (32) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    NOT enables peptidase activity IKR
    Inferred from Key Residues
    more info
    		  
    NOT enables serine-type endopeptidase activity IKR
    Inferred from Key Residues
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in negative regulation of female receptivity, post-mating IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in sexual reproduction HEP PubMed 
    involved_in sperm storage IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular space HDA PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    aquarius
    Names
    CG14061-PA
    aqrs-PA

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      28756999..28758234 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_143375.2 → NP_651632.2  aquarius [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_651632.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q4V3V9, Q9VAT7
      Related
      FBpp0084682
      Conserved Domains (2) summary
      pfam00089
      Location:82 → 290
      Trypsin; Trypsin
      cl21584
      Location:83 → 268
      Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VAT7 Q9VAT7

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Other Literature Sources
    Molecular Biology Databases
    Research Materials
    Tools