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    scyl scylla [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 39270, updated on 9-Dec-2024

    Summary

    Official Symbol
    scylprovided by FlyBase
    Official Full Name
    scyllaprovided by FlyBase
    Primary source
    FLYBASE:FBgn0041094
    Locus tag
    Dmel_CG7590
    See related
    AllianceGenome:FB:FBgn0041094
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    7590; anon-WO0118547.215; CG7590; Dmel\CG7590; scy; Scyl; Scylla
    Summary
    Involved in several processes, including head involution; regulation of TOR signaling; and response to oxidative stress. Predicted to be located in cytoplasm. Is expressed in border follicle cell; centripetal follicle cell; follicle cell; and wing disc. Orthologous to human DDIT4 (DNA damage inducible transcript 4) and DDIT4L (DNA damage inducible transcript 4 like). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See scyl in Genome Data Viewer
    Location:
    68B4-68C1; 3-35 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (11252307..11256172)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (11245407..11249272)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR44715 Neighboring gene long non-coding RNA:CR44717 Neighboring gene long non-coding RNA:CR44716 Neighboring gene long non-coding RNA:CR44720 Neighboring gene long non-coding RNA:CR45404

    Genomic regions, transcripts, and products

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by FlyBase

    Process Evidence Code Pubs
    involved_in apoptotic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in apoptotic process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in head involution IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in negative regulation of growth IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    involved_in negative regulation of signal transduction IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in regulation of TOR signaling IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in regulation of TOR signaling IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in response to oxidative stress IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in sexual reproduction IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytoplasm ISS
    Inferred from Sequence or Structural Similarity
    more info
     

    General protein information

    Preferred Names
    scylla
    Names
    CG7590-PA
    CG7590-PC
    scyl-PA
    scyl-PC

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      11252307..11256172
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_206321.2NP_996043.2  scylla, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_996043.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      B9EQR6, Q5U1B7, Q8SY44, Q9NHN4, Q9VTH4
      Conserved Domains (1) summary
      pfam07809
      Location:139252
      RTP801_C; RTP801 C-terminal region
    2. NM_140199.4NP_648456.2  scylla, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_648456.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      B9EQR6, Q5U1B7, Q8SY44, Q9NHN4, Q9VTH4
      Related
      FBpp0075899
      Conserved Domains (1) summary
      pfam07809
      Location:139252
      RTP801_C; RTP801 C-terminal region