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    fimG type 1 fimbriae minor subunit FimG [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 948846, updated on 17-Dec-2024

    Summary

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    Official Symbol
    fimG
    Official Full Name
    type 1 fimbriae minor subunit FimG
    Primary source
    ECOCYC:EG10314
    Locus tag
    b4319
    See related
    ASAP:ABE-0014155
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK4310
    Summary
    One of 25 FimA homologs in EcoGene. [More information is available at EcoGene: EG10314]. FimG is a minor component of the type 1 fimbriae in Escherichia coli Two-dimensional gel electrophoresis indicated that FimG has a molecular weight of 17.0 kDa and exists in a 1:100 ratio with the major fimbrial subunit, FimA . [More information is available at EcoCyc: EG10314].
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    Genomic context

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    Sequence:
    NC_000913.3 (4548285..4548788)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene type I fimbriae usher protein Neighboring gene type 1 fimbriae minor subunit FimF Neighboring gene type 1 fimbriae D-mannose specific adhesin Neighboring gene fructuronate transporter

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The influence of disulfide bonds on the mechanical stability of proteins is context dependent. Manteca A, et al. J Biol Chem, 2017 Aug 11. PMID 28642368, Free PMC Article
    2. Three fim genes required for the regulation of length and mediation of adhesion of Escherichia coli type 1 fimbriae. Klemm P, et al. Mol Gen Genet, 1987 Jul. PMID 2890081
    3. Infinite kinetic stability against dissociation of supramolecular protein complexes through donor strand complementation. Puorger C, et al. Structure, 2008 Apr. PMID 18400183
    4. Pilus chaperones represent a new type of protein-folding catalyst. Vetsch M, et al. Nature, 2004 Sep 16. PMID 15372038
    5. Structural and energetic basis of folded-protein transport by the FimD usher. Geibel S, et al. Nature, 2013 Apr 11. PMID 23579681, Free PMC Article

    See all (41) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Data suggest that disulfide bonds can alter mechanical stability of proteins in different ways depending on properties of system. Disulfide-bonded E coli FimG (minor component of type 1 fimbriae) undergoes a 30% increase in its mechanical stability compared with its reduced counterpart. Unfolding force of human titan I91 domain exhibits decrease of 15% relative to the wild-type form.
      Title: The influence of disulfide bonds on the mechanical stability of proteins is context dependent.
    2. The complex between the pilus subunit FimG and the donor strand peptide of the subunit FimF shows an extrapolated dissociation half-life of 3 x 10(9) years.
      Title: Infinite kinetic stability against dissociation of supramolecular protein complexes through donor strand complementation.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cell adhesion IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in cell adhesion IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in cell adhesion involved in single-species biofilm formation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in cell-substrate adhesion IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in mechanosensory behavior IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in pilus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in pilus IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in pilus tip IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    type 1 fimbriae minor subunit FimG

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      4548285..4548788
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_418739.1 type 1 fimbriae minor subunit FimG [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_418739.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A061KCG9, A0A0A1AGR2, A0A0E2KXQ6, A0A0H0L1T7, A0A0H3MNP2, A0A0J3ZBZ1, A0A0K4BDM8, A0A210GQH8, A0A3L5GXI8, A0A7T2N281, A0AAI9B7S6, A0AAN4NNA8, A7ZVL5, B7MMK9, B7NGX4
      Conserved Domains (1) summary
      COG3539
      Location:23 → 166
      FimA; Pilin (type 1 fimbria component protein) [Cell motility]
    Nucleotide Protein
    Heading Accession and Version

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