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    fliT flagellar biosynthesis protein FliT [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 946433, updated on 3-Dec-2024

    Summary

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    Official Symbol
    fliT
    Official Full Name
    flagellar biosynthesis protein FliT
    Primary source
    ECOCYC:EG11389
    Locus tag
    b1926
    See related
    ASAP:ABE-0006411
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK1925
    Summary
    Flagellar regulon. [More information is available at EcoGene: EG11389]. FliT, along with FliS and FlgN, are cytoplasmic, substrate-specific chaperones of the flagellar export system. [More information is available at EcoCyc: EG11389].
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    Genomic context

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    Sequence:
    NC_000913.3 (2005713..2006078)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene flagellar filament capping protein Neighboring gene flagellar biosynthesis protein FliS Neighboring gene alpha-amylase Neighboring gene lipoprotein YedD

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Functional analysis of the flagellar genes in the fliD operon of Salmonella typhimurium. Yokoseki T, et al. Microbiology (Reading), 1995 Jul. PMID 7551038
    2. Escherichia coli flagellar genes as target sites for integration and expression of genetic circuits. Juhas M, et al. PLoS One, 2014. PMID 25350000, Free PMC Article
    3. Benchmarking yeast two-hybrid systems using the interactions of bacterial motility proteins. Rajagopala SV, et al. Proteomics, 2009 Dec. PMID 19834901, Free PMC Article
    4. FliT acts as an anti-FlhD2C2 factor in the transcriptional control of the flagellar regulon in Salmonella enterica serovar typhimurium. Yamamoto S, et al. J Bacteriol, 2006 Sep. PMID 16952964, Free PMC Article
    5. Excretion of the anti-sigma factor through a flagellar substructure couples flagellar gene expression with flagellar assembly in Salmonella typhimurium. Kutsukake K. Mol Gen Genet, 1994 Jun 15. PMID 8028576

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. analysis of integration and expression at four candidate loci, fliD, fliS, fliT, and fliY, of the E. coli flagellar region 3a
      Title: Escherichia coli flagellar genes as target sites for integration and expression of genetic circuits.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in bacterial-type flagellum organization IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within bacterial-type flagellum-dependent cell motility IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in negative regulation of bacterial-type flagellum assembly IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in protein folding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    flagellar biosynthesis protein FliT

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      2005713..2006078
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_416436.1 flagellar biosynthesis protein FliT [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_416436.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A5B9AJ01
      Conserved Domains (1) summary
      PRK10548
      Location:1 → 121
      PRK10548; flagella biosynthesis regulatory protein FliT
    Nucleotide Protein
    Heading Accession and Version

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