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    hcaR DNA-binding transcriptional dual regulator HcaR [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 947000, updated on 3-Dec-2024

    Summary

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    Official Symbol
    hcaR
    Official Full Name
    DNA-binding transcriptional dual regulator HcaR
    Primary source
    ECOCYC:G7331
    Locus tag
    b2537
    See related
    ASAP:ABE-0008351
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK2534; phdR; yfhT
    Summary
    Hydrocinnamic acid is a synonym for 3-phenylpropionic acid. [More information is available at EcoGene: EG13455].
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    Genomic context

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    Sequence:
    NC_000913.3 (2668006..2668896, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene putative peptidase Neighboring gene stationary phase-inducible protein CsiE Neighboring gene putative 3-phenylpropionate transporter Neighboring gene protein IroK Neighboring gene putative 3-phenylpropionate/cinnamate dioxygenase subunit alpha Neighboring gene putative 3-phenylpropionate/cinnamate dioxygenase subunit beta Neighboring gene putative 3-phenylpropionate/cinnamate dioxygenase ferredoxin subunit Neighboring gene 2,3-dihydroxy-2,3-dihydrophenylpropionate dehydrogenase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Regulation of the early steps of 3-phenylpropionate catabolism in Escherichia coli. Turlin E, et al. J Mol Microbiol Biotechnol, 2001 Jan. PMID 11200225
    2. 3-phenylpropionate catabolism and the Escherichia coli oxidative stress response. Turlin E, et al. Res Microbiol, 2005 Apr. PMID 15808934
    3. Characterization of the hca cluster encoding the dioxygenolytic pathway for initial catabolism of 3-phenylpropionic acid in Escherichia coli K-12. Díaz E, et al. J Bacteriol, 1998 Jun. PMID 9603882, Free PMC Article
    4. Identification of stress-related proteins in Escherichia coli using the pollutant cis-dichloroethylene. Lee J, et al. J Appl Microbiol, 2010 Jun. PMID 19919618
    5. Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110. Hayashi K, et al. Mol Syst Biol, 2006. PMID 16738553, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables DNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables DNA-binding transcription factor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables DNA-binding transcription factor activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables DNA-binding transcription factor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within negative regulation of DNA-templated transcription IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within positive regulation of DNA-templated transcription IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in regulation of DNA-templated transcription IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of protein-DNA complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    DNA-binding transcriptional dual regulator HcaR

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      2668006..2668896 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_417032.1 DNA-binding transcriptional dual regulator HcaR [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_417032.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A1X3JFL1, A0A6N8QTI6
      Conserved Domains (1) summary
      PRK09906
      Location:1 → 296
      PRK09906; DNA-binding transcriptional regulator HcaR; Provisional
    Nucleotide Protein
    Heading Accession and Version

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