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    mhpT 3-hydroxyphenylpropionate/3-hydroxycinnamate:H(+) symporter [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 944997, updated on 17-Dec-2024

    Summary

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    Official Symbol
    mhpT
    Official Full Name
    3-hydroxyphenylpropionate/3-hydroxycinnamate:H(+) symporter
    Primary source
    ECOCYC:G6206
    Locus tag
    b0353
    See related
    ASAP:ABE-0001213
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK0350; yaiK
    Summary
    Major Facilitator Superfamily (MFS). [More information is available at EcoGene: EG13293]. MhpT is a putative 3-hydroxyphenylpropionic acid transporter. [More information is available at EcoCyc: G6206].
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    Genomic context

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    Sequence:
    NC_000913.3 (375459..376670)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene 2-hydroxypentadienoate hydratase Neighboring gene acetaldehyde dehydrogenase (acetylating) MhpF Neighboring gene 4-hydroxy-2-oxovalerate aldolase Neighboring gene DUF2058 domain-containing protein YaiL Neighboring gene S-formylglutathione hydrolase FrmB

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Biodegradation of aromatic compounds by Escherichia coli. Díaz E, et al. Microbiol Mol Biol Rev, 2001 Dec. PMID 11729263, Free PMC Article
    2. Genetic characterization and expression in heterologous hosts of the 3-(3-hydroxyphenyl)propionate catabolic pathway of Escherichia coli K-12. Ferrández A, et al. J Bacteriol, 1997 Apr. PMID 9098055, Free PMC Article
    3. Microbial drug efflux proteins of the major facilitator superfamily. Saidijam M, et al. Curr Drug Targets, 2006 Jul. PMID 16842212
    4. The major facilitator superfamily. Saier MH Jr, et al. J Mol Microbiol Biotechnol, 1999 Nov. PMID 10943556
    5. A major superfamily of transmembrane facilitators that catalyse uniport, symport and antiport. Marger MD, et al. Trends Biochem Sci, 1993 Jan. PMID 8438231

    See all (15) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables 3-hydroxyphenyl propionate:proton symporter activity EXP
    Inferred from Experiment
    more info
    		 PubMed 
    enables symporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in 3-hydroxyphenyl propanoate transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within 3-hydroxyphenylpropionic acid transmembrane transport EXP
    Inferred from Experiment
    more info
    		 PubMed 
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in plasma membrane RCA
    inferred from Reviewed Computational Analysis
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    3-hydroxyphenylpropionate/3-hydroxycinnamate:H(+) symporter

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      375459..376670
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_414887.2 3-hydroxyphenylpropionate/3-hydroxycinnamate:H(+) symporter [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_414887.2

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A376FR84
      Conserved Domains (1) summary
      PRK11551
      Location:13 → 401
      PRK11551; putative 3-hydroxyphenylpropionic transporter MhpT; Provisional
    Nucleotide Protein
    Heading Accession and Version

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