U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    psd phosphatidylserine decarboxylase proenzyme [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 948673, updated on 17-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    psd
    Official Full Name
    phosphatidylserine decarboxylase proenzyme
    Primary source
    ECOCYC:EG10775
    Locus tag
    b4160
    See related
    ASAP:ABE-0013623
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK4156
    Summary
    N-terminal of alpha subunit (Ser254) is midified to pyruvic acid, a point mutation here results in reduced processing. [More information is available at EcoGene: EG10775]. This subunit contains the pyruvate prosthetic group. [More information is available at EcoCyc: EG10775].
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    Sequence:
    NC_000913.3 (4389392..4390360, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein YjeN Neighboring gene DUF2645 domain-containing inner membrane protein YjeO Neighboring gene miniconductance mechanosensitive channel MscM Neighboring gene ribosome small subunit-dependent GTPase A Neighboring gene oligoribonuclease

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Structural Basis for Phosphatidylethanolamine Biosynthesis by Bacterial Phosphatidylserine Decarboxylase. Watanabe Y, et al. Structure, 2020 Jul 7. PMID 32402247
    2. Increased synthesis of phosphatidylserine decarboxylase in a strain of Escherichia coli bearing a hybrid plasmid. Altered association of enzyme with the membrane. Tyhach RJ, et al. J Biol Chem, 1979 Feb 10. PMID 368058
    3. Biogenesis of membrane lipids: mutants of Escherichia coli with temperature-sensitive phosphatidylserine decarboxylase. Hawrot E, et al. Proc Natl Acad Sci U S A, 1975 Mar. PMID 1093166, Free PMC Article
    4. Phosphatidylserine decarboxylase from Escherichia coli. Dowhan W, et al. Methods Enzymol, 1992. PMID 1495415
    5. Kinetics and protein subunit interactions of Escherichia coli phosphatidylserine decarboxylase in detergent solution. Rizzolo LJ. Biochemistry, 1981 Feb 17. PMID 7011377

    See all (18) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. N-terminus verified by Edman degradation on complete protein
      Title: Structural characterization of Escherichia coli phosphatidylserine decarboxylase.
    Submit: New GeneRIF Correction

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables carboxy-lyase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables phosphatidylserine decarboxylase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables phosphatidylserine decarboxylase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables phosphatidylserine decarboxylase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein homodimerization activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in phosphatidylethanolamine biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in phosphatidylethanolamine biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within phosphatidylethanolamine biosynthetic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in phospholipid biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within protein autoprocessing IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within zymogen activation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    phosphatidylserine decarboxylase proenzyme
    NP_418584.1

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      4389392..4390360 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_418584.1 phosphatidylserine decarboxylase proenzyme [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_418584.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A5B9ANA1, A0A6M9WXA7, A0AAI9H4R7
      Conserved Domains (1) summary
      PRK00044
      Location:1 → 289
      psd; phosphatidylserine decarboxylase; Reviewed
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.