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    rspA mandelate racemase/muconate lactonizing enzyme family protein RspA [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 946126, updated on 3-Dec-2024

    Summary

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    Official Symbol
    rspA
    Official Full Name
    mandelate racemase/muconate lactonizing enzyme family protein RspA
    Primary source
    ECOCYC:G6839
    Locus tag
    b1581
    See related
    ASAP:ABE-0005275
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK1576
    Summary
    Overproduced RspA may degrade HSL. [More information is available at EcoGene: EG12451]. The RspA protein is a bifunctional dehydratase that utilizes both D-mannonate and D-altronate as substrates . [More information is available at EcoCyc: G6839].
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    Genomic context

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    Sequence:
    NC_000913.3 (1653927..1655141, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene protein YnfP Neighboring gene putative zinc-binding dehydrogenase RspB Neighboring gene putative transporter YnfA Neighboring gene DUF1283 domain-containing protein YnfB

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Homocysteine thiolactone is a positive effector of sigma(S) levels in Escherichia coli. Goodrich-Blair H, et al. FEMS Microbiol Lett, 2000 Apr 15. PMID 10754234
    2. Quantitative whole-genome analysis of DNA-protein interactions by in vivo methylase protection in E. coli. Tavazoie S, et al. Nat Biotechnol, 1998 Jun. PMID 9624689
    3. Sensing starvation: a homoserine lactone--dependent signaling pathway in Escherichia coli. Huisman GW, et al. Science, 1994 Jul 22. PMID 7545940
    4. A 570-kb DNA sequence of the Escherichia coli K-12 genome corresponding to the 28.0-40.1 min region on the linkage map. Aiba H, et al. DNA Res, 1996 Dec 31. PMID 9097039
    5. Large-scale identification of protein-protein interaction of Escherichia coli K-12. Arifuzzaman M, et al. Genome Res, 2006 May. PMID 16606699, Free PMC Article

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables hydro-lyase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables magnesium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables mannonate dehydratase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in amino acid catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in carbohydrate catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    mandelate racemase/muconate lactonizing enzyme family protein RspA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      1653927..1655141 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_416098.1 mandelate racemase/muconate lactonizing enzyme family protein RspA [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_416098.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A2X1QJ22, A0A828P558
      Conserved Domains (1) summary
      PRK15072
      Location:1 → 404
      PRK15072; D-galactonate dehydratase family protein
    Nucleotide Protein
    Heading Accession and Version

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