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    zitB Zn(2(+))/Cd(2(+))/Ni(2(+))/Cu(2(+)) exporter [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 945348, updated on 3-Dec-2024

    Summary

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    Official Symbol
    zitB
    Official Full Name
    Zn(2(+))/Cd(2(+))/Ni(2(+))/Cu(2(+)) exporter
    Primary source
    ECOCYC:G6393
    Locus tag
    b0752
    See related
    ASAP:ABE-0002549
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK0741; ybgR
    Summary
    ZitB (formerly known as YbgR) is a probable Zn2+ transporter. [More information is available at EcoCyc: G6393].
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    Genomic context

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    Sequence:
    NC_000913.3 (783882..784823, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene tRNA-Lys Neighboring gene quinolinate synthase Neighboring gene nicotinamide riboside transporter Neighboring gene PF13985 family protein YbgS Neighboring gene 3-deoxy-7-phosphoheptulonate synthase, Phe-sensitive

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Probing metal ion substrate-binding to the E. coli ZitB exporter in native membranes by solid state NMR. Rahman M, et al. Mol Membr Biol, 2008 Dec. PMID 19039702
    2. Characteristics of zinc transport by two bacterial cation diffusion facilitators from Ralstonia metallidurans CH34 and Escherichia coli. Anton A, et al. J Bacteriol, 2004 Nov. PMID 15516561, Free PMC Article
    3. Kinetic study of the antiport mechanism of an Escherichia coli zinc transporter, ZitB. Chao Y, et al. J Biol Chem, 2004 Mar 26. PMID 14715669
    4. ZitB (YbgR), a member of the cation diffusion facilitator family, is an additional zinc transporter in Escherichia coli. Grass G, et al. J Bacteriol, 2001 Aug. PMID 11443104, Free PMC Article
    5. Experimentally based topology models for E. coli inner membrane proteins. Rapp M, et al. Protein Sci, 2004 Apr. PMID 15044727, Free PMC Article

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Charged or polar amino acyl residues located within or adjacent to membrane-spanning regions of the protein were essential for the full function of the proteins, cation export or for proton import
      Title: Characteristics of zinc transport by two bacterial cation diffusion facilitators from Ralstonia metallidurans CH34 and Escherichia coli.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables zinc ion transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables zinc ion transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables zinc ion transmembrane transporter activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in zinc ion transmembrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in zinc ion transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within zinc ion transport IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Zn(2(+))/Cd(2(+))/Ni(2(+))/Cu(2(+)) exporter

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      783882..784823 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_415273.1 Zn(2(+))/Cd(2(+))/Ni(2(+))/Cu(2(+)) exporter [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_415273.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A5D8MSV4
      Conserved Domains (1) summary
      PRK03557
      Location:1 → 312
      PRK03557; CDF family zinc transporter ZitB
    Nucleotide Protein
    Heading Accession and Version

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