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    elbB low activity glyoxalase ElbB [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 947903, updated on 3-Dec-2024

    Summary

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    Official Symbol
    elbB
    Official Full Name
    low activity glyoxalase ElbB
    Primary source
    ECOCYC:EG11383
    Locus tag
    b3209
    See related
    ASAP:ABE-0010532
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK3198; elb2; s27a; yhbL; yzzB
    Summary
    Variously called C56 peptidase family, PfpI/HchA peptidase/chaperone family, DJ-1/PARK7 superfamily. [More information is available at EcoGene: EG11383]. The ElbB protein cross-reacts with an antibody prepared against a peptide of the 2.2 region of sigma 70 and sigma 32 and was therefore originally named sigma cross-reacting protein 27A (SCRP-27A) . elbB was identified in a mutant screen designed to identify genes involved in the biosynthesis of isopentenyl diphosphate, a precursor of isoprenoids . [More information is available at EcoCyc: EG11383].
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    Genomic context

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    Sequence:
    NC_000913.3 (3349806..3350459, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene RNase adaptor protein RapZ Neighboring gene phosphorelay protein NPr Neighboring gene protein kinase-like domain-containing protein YrbL Neighboring gene peptidoglycan glycosyltransferase MtgA Neighboring gene ncRNA Neighboring gene sensor histidine kinase ArcB Neighboring gene radical SAM family oxidoreductase YhcC

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Identification of genes affecting lycopene formation in Escherichia coli transformed with carotenoid biosynthetic genes: candidates for early genes in isoprenoid biosynthesis. Hemmi H, et al. J Biochem, 1998 Jun. PMID 9603997
    2. Identification of Escherichia coli proteins cross-reacting with antibodies against region 2.2 peptide of RNA polymerase sigma subunit. Ueshima R, et al. Biochem Biophys Res Commun, 1992 Apr 30. PMID 1575737
    3. The atomic resolution crystal structure of the YajL (ThiJ) protein from Escherichia coli: a close prokaryotic homologue of the Parkinsonism-associated protein DJ-1. Wilson MA, et al. J Mol Biol, 2005 Oct 28. PMID 16181642
    4. Identification of functional subclasses in the DJ-1 superfamily proteins. Wei Y, et al. PLoS Comput Biol, 2007 Jan 26. PMID 17257049, Free PMC Article
    5. Multi-dimensional gene target search for improving lycopene biosynthesis in Escherichia coli. Jin YS, et al. Metab Eng, 2007 Jul. PMID 17509919

    See all (19) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Purified YajL, YhbO and ElbB exhibited glyoxalase activity with different substrate specificities, optimal pHs and metal effects.
      Title: Characterization of the Escherichia coli YajL, YhbO and ElbB glyoxalases.
    2. N-terminus verified by Edman degradation on complete protein
      Title: Identification of Escherichia coli proteins cross-reacting with antibodies against region 2.2 peptide of RNA polymerase sigma subunit.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables lyase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within isoprenoid biosynthetic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within positive regulation of isoprenoid metabolic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytosol IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    low activity glyoxalase ElbB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      3349806..3350459 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_417676.2 low activity glyoxalase ElbB [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_417676.2

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A2X1MQU0, A0A376MKI9, A0A8T5ZIS0
      Conserved Domains (1) summary
      PRK11780
      Location:1 → 217
      PRK11780; isoprenoid biosynthesis glyoxalase ElbB
    Nucleotide Protein
    Heading Accession and Version

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