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    ubiB ubiquinone biosynthesis protein UbiB [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 948322, updated on 14-Jan-2025

    Summary

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    Official Symbol
    ubiB
    Official Full Name
    ubiquinone biosynthesis protein UbiB
    Primary source
    ECOCYC:EG11476
    Locus tag
    b3835
    See related
    ASAP:ABE-0012539
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    aarF; ECK3829; yigQ; yigR; yigS
    Summary
    [More information is available at EcoGene: EG11476]. ubiB is thought to encode 2-octaprenylphenol hydroxylase, which catalyzes the first hydroxylation step in the ubiquinone biosynthesis pathway. [More information is available at EcoCyc: EG11476].
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    Genomic context

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    Sequence:
    NC_000913.3 (4020226..4021866)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene putative recombination limiting protein RmuC Neighboring gene bifunctional 2-octaprenyl-6-methoxy-1,4-benzoquinol methylase and demethylmenaquinone methyltransferase Neighboring gene ubiquinone biosynthesis accessory factor UbiJ Neighboring gene ncRNA Neighboring gene twin arginine protein translocation system - TatA protein Neighboring gene twin arginine protein translocation system - TatB protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Biosynthesis of ubiquinone in Escherichia coli K-12: location of genes affecting the metabolism of 3-octaprenyl-4-hydroxybenzoic acid and 2-octaprenylphenol. Cox GB, et al. J Bacteriol, 1969 Aug. PMID 4897112, Free PMC Article
    2. Pathway for ubiquinone biosynthesis in Escherichia coli K-12: gene-enzyme relationships and intermediates. Young IG, et al. J Bacteriol, 1973 Apr. PMID 4572721, Free PMC Article
    3. Random cloning of bent DNA segments from Escherichia coli chromosome and primary characterization of their structures. Mizuno T. Nucleic Acids Res, 1987 Sep 11. PMID 3309887, Free PMC Article
    4. Alternative hydroxylases for the aerobic and anaerobic biosynthesis of ubiquinone in Escherichia coli. Alexander K, et al. Biochemistry, 1978 Oct 31. PMID 365223
    5. Biosynthesis of menaquinone (vitamin K2) and ubiquinone (coenzyme Q): a perspective on enzymatic mechanisms. Meganathan R. Vitam Horm, 2001. PMID 11153266

    See all (15) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of ubiquinone biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in ubiquinone biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within ubiquinone biosynthetic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    ubiquinone biosynthesis protein UbiB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      4020226..4021866
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_418279.1 ubiquinone biosynthesis protein UbiB [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_418279.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A5B9AN59
      Conserved Domains (1) summary
      PRK04750
      Location:3 → 545
      ubiB; putative ubiquinone biosynthesis protein UbiB; Reviewed
    Nucleotide Protein
    Heading Accession and Version

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