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    fadI 3-ketoacyl-CoA thiolase FadI [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 948823, updated on 3-Dec-2024

    Summary

    Official Symbol
    fadI
    Official Full Name
    3-ketoacyl-CoA thiolase FadI
    Primary source
    ECOCYC:G7213
    Locus tag
    b2342
    See related
    ASAP:ABE-0007725
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK2336; yfcY
    Summary
    Also known as beta-oxidation complex II. [More information is available at EcoGene: EG14128]. During anaerobic beta-oxidation of fatty acids FadI, FadJ, and FadK serve functions parallel to those of FadA, FadB, and FadD in the aerobic pathway . [More information is available at EcoCyc: G7213].
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    Genomic context

    Sequence:
    NC_000913.3 (2459159..2460469, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene putative fimbrial protein YfcV Neighboring gene phosphohistidine phosphatase SixA Neighboring gene 3-hydroxyacyl-CoA dehydrogenase FadJ Neighboring gene DUF406 domain-containing protein YfcZ Neighboring gene long-chain fatty acid outer membrane channel/bacteriophage T2 receptor

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by EcoCyc

    Process Evidence Code Pubs
    involved_in fatty acid beta-oxidation IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in fatty acid beta-oxidation IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within fatty acid beta-oxidation IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    acts_upstream_of_or_within fatty acid beta-oxidation, unsaturated, even number IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in fatty acid metabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in lipid catabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in small molecule metabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in cytosol IDA
    Inferred from Direct Assay
    more info
    PubMed 
    part_of fatty acid beta-oxidation multienzyme complex IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    3-ketoacyl-CoA thiolase FadI
    NP_416844.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      2459159..2460469 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_416844.1 3-ketoacyl-CoA thiolase FadI [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_416844.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A2H4TX56
      Conserved Domains (1) summary
      PRK08963
      Location:9436
      fadI; 3-ketoacyl-CoA thiolase; Reviewed