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    flgL flagellar hook-filament junction protein 2 [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 945646, updated on 17-Dec-2024

    Summary

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    Official Symbol
    flgL
    Official Full Name
    flagellar hook-filament junction protein 2
    Primary source
    ECOCYC:EG11545
    Locus tag
    b1083
    See related
    ASAP:ABE-0003666
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK1068; flaT
    Summary
    Overexpression causes mucoidy, decreases the amount of biofilm formed, and prevents flagella formation. [More information is available at EcoGene: EG11545]. Experiments in Salmonella typhimurium using antibodies against the flagellar proteins FlgK and FlgL identify them as junction proteins which connect the filament to the hook . [More information is available at EcoCyc: EG11545].
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    Genomic context

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    Sequence:
    NC_000913.3 (1140033..1140986)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene flagellar P-ring protein Neighboring gene putative peptidoglycan hydrolase FlgJ Neighboring gene flagellar hook-filament junction protein 1 Neighboring gene ncRNA Neighboring gene ribonuclease E Neighboring gene DUF2655 domain-containing protein YceQ

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Cloning and analysis of the entire Escherichia coli ams gene. ams is identical to hmp1 and encodes a 114 kDa protein that migrates as a 180 kDa protein. Casarégola S, et al. J Mol Biol, 1992 Nov 5. PMID 1447789
    2. Localization and stoichiometry of hook-associated proteins within Salmonella typhimurium flagella. Ikeda T, et al. J Bacteriol, 1987 Mar. PMID 3546266, Free PMC Article
    3. Assigning protein functions by comparative genome analysis: protein phylogenetic profiles. Pellegrini M, et al. Proc Natl Acad Sci U S A, 1999 Apr 13. PMID 10200254, Free PMC Article
    4. Genetic analysis of Escherichia coli K-12 region I flagellar mutants. Komeda Y, et al. J Bacteriol, 1977 Sep. PMID 330498, Free PMC Article
    5. Genes for the hook-basal body proteins of the flagellar apparatus in Escherichia coli. Komeda Y, et al. J Bacteriol, 1978 May. PMID 350831, Free PMC Article

    See all (22) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables structural molecule activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in bacterial-type flagellum-dependent cell motility IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in bacterial-type flagellum IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in bacterial-type flagellum hook IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    flagellar hook-filament junction protein 2

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      1140033..1140986
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_415601.1 flagellar hook-filament junction protein 2 [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_415601.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A376RK06
      Conserved Domains (1) summary
      PRK08027
      Location:1 → 317
      flgL; flagellar hook-filament junction protein FlgL
    Nucleotide Protein
    Heading Accession and Version

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