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    ATP7 F1F0 ATP synthase subunit d [ Saccharomyces cerevisiae S288C ]

    Gene ID: 853853, updated on 9-Dec-2024

    Summary

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    Official Symbol
    ATP7
    Official Full Name
    F1F0 ATP synthase subunit d
    Primary source
    SGD:S000001499
    Locus tag
    YKL016C
    See related
    AllianceGenome:SGD:S000001499; FungiDB:YKL016C; VEuPathDB:YKL016C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Contributes to proton-transporting ATP synthase activity, rotational mechanism. Involved in proton motive force-driven ATP synthesis. Located in mitochondrion. Part of proton-transporting ATP synthase, stator stalk. Orthologous to human ATP5PD (ATP synthase peripheral stalk subunit d). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See ATP7 in Genome Data Viewer
    Location:
    chromosome: XI
    Exon count:
    1
    Sequence:
    Chromosome: XI; NC_001143.9 (407465..407989, complement)

    Chromosome XI - NC_001143.9Genomic Context describing neighboring genes Neighboring gene WD-repeat containing protein SWD2 Neighboring gene ATP-dependent 5'-3' DNA helicase HCS1 Neighboring gene Put3p Neighboring gene Urb1p

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001143.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. ATP synthase of yeast mitochondria. Characterization of subunit d and sequence analysis of the structural gene ATP7. Norais N, et al. J Biol Chem, 1991 Sep 5. PMID 1832157
    2. Over-expression of the yeast ATP synthase subunit D in Escherichia coli: use of polyclonal antibodies directed against recombinant subunit D. Norais N, et al. Biochem Biophys Res Commun, 1994 Apr 29. PMID 8179622
    3. Single copies of subunits d, oligomycin-sensitivity conferring protein, and b are present in the Saccharomyces cerevisiae mitochondrial ATP synthase. Bateson M, et al. J Biol Chem, 1999 Mar 12. PMID 10066811
    4. The second stalk of the yeast ATP synthase complex: identification of subunits showing cross-links with known positions of subunit 4 (subunit b). Soubannier V, et al. Biochemistry, 1999 Nov 9. PMID 10555984
    5. Topological and functional study of subunit h of the F1Fo ATP synthase complex in yeast Saccharomyces cerevisiae. Fronzes R, et al. Biochemistry, 2003 Oct 21. PMID 14556635

    See all (87) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables proton transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    contributes_to proton-transporting ATP synthase activity, rotational mechanism IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    contributes_to proton-transporting ATP synthase activity, rotational mechanism IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    contributes_to proton-transporting ATP synthase activity, rotational mechanism IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in ATP biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in proton motive force-driven ATP synthesis IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in proton motive force-driven ATP synthesis IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in proton motive force-driven ATP synthesis IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in proton motive force-driven ATP synthesis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in proton transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in mitochondrial inner membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in mitochondrion HDA PubMed 
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of proton-transporting ATP synthase complex, coupling factor F(o) IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of proton-transporting ATP synthase, stator stalk IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of proton-transporting ATP synthase, stator stalk IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    F1F0 ATP synthase subunit d
    NP_012909.3
    • Subunit d of the stator stalk of mitochondrial F1F0 ATP synthase; F1F0 ATP synthase is a large, evolutionarily conserved enzyme complex required for ATP synthesis

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001143.9 Reference assembly

      Range
      407465..407989 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001179582.3 → NP_012909.3  TPA: F1F0 ATP synthase subunit d [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_012909.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VXS0, P30902
      UniProtKB/TrEMBL
      B3LR69, B5VMD9, G2WI15, N1P7Y9
      Conserved Domains (1) summary
      pfam05873
      Location:5 → 145
      Mt_ATP-synt_D; ATP synthase D chain, mitochondrial (ATP5H)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P30902.2

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