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    rimL ribosomal-protein-L12-serine N-acetyltransferase [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 945998, updated on 17-Dec-2024

    Summary

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    Official Symbol
    rimL
    Official Full Name
    ribosomal-protein-L12-serine N-acetyltransferase
    Primary source
    ECOCYC:EG10853
    Locus tag
    b1427
    See related
    ASAP:ABE-0004763
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK1420
    Summary
    Ribosome-associated protein (Jiang, 2007). [More information is available at EcoGene: EG10853]. RimL is the acetyl transferase that acetylates the N-terminal serine residue of ribosomal protein L12, converting it into its modified form, L7 . [More information is available at EcoCyc: EG10853].
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    Genomic context

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    Sequence:
    NC_000913.3 (1498938..1499477)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene glucans biosynthesis protein D Neighboring gene DUF465 domain-containing protein YdcH Neighboring gene putative acyltransferase YdcK Neighboring gene tellurite resistance protein Neighboring gene tellurite methyltransferase Neighboring gene DUF3313 domain-containing lipoprotein YdcL

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The RimL transacetylase provides resistance to translation inhibitor microcin C. Kazakov T, et al. J Bacteriol, 2014 Oct. PMID 25002546, Free PMC Article
    2. Studies of the in vitro Nalpha-acetyltransferase activities of E. coli RimL protein. Miao L, et al. Biochem Biophys Res Commun, 2007 Jun 8. PMID 17445774
    3. Activity-based substrate profiling for Gcn5-related N-acetyltransferases: the use of chloroacetyl-coenzyme A to identify protein substrates. Yu M, et al. J Am Chem Soc, 2006 Dec 6. PMID 17131985, Free PMC Article
    4. Ribosomal protein modification in Escherichia coli. III. Studies of mutants lacking an acetylase activity specific for protein L12. Isono S, et al. Mol Gen Genet, 1981. PMID 7038378
    5. The primary structure of an acidic protein from 50-S ribosomes of Escherichia coli which is involved in GTP hydrolysis dependent on elongation factors G and T. Terhorst C, et al. Eur J Biochem, 1973 Apr 2. PMID 4573678

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. RimL transacetylase provides resistance to translation inhibitor microcin C.
      Title: The RimL transacetylase provides resistance to translation inhibitor microcin C.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables N-acetyltransferase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables acyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables acyltransferase activity, transferring groups other than amino-acyl groups IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables peptide alpha-N-acetyltransferase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables peptide-alanine-alpha-N-acetyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables peptide-alanine-alpha-N-acetyltransferase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables peptide-serine-alpha-N-acetyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables peptide-serine-alpha-N-acetyltransferase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within protein modification process IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    ribosomal-protein-L12-serine N-acetyltransferase

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      1498938..1499477
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_415944.1 ribosomal-protein-L12-serine N-acetyltransferase [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_415944.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      Q1RBY9
      Conserved Domains (1) summary
      PRK10151
      Location:1 → 179
      PRK10151; 50S ribosomal protein L7/L12-serine acetyltransferase
    Nucleotide Protein
    Heading Accession and Version

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