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    rhtC L-threonine exporter [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 948317, updated on 3-Dec-2024

    Summary

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    Official Symbol
    rhtC
    Official Full Name
    L-threonine exporter
    Primary source
    ECOCYC:EG11468
    Locus tag
    b3823
    See related
    ASAP:ABE-0012487
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK3817; yigJ
    Summary
    RhtC is a LysE superfamily exporter. [More information is available at EcoGene: EG11468]. RhtC is a probable threonine efflux transporter. [More information is available at EcoCyc: EG11468].
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    Genomic context

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    Sequence:
    NC_000913.3 (4007757..4008377)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene outer membrane phospholipase A Neighboring gene ATP-dependent DNA helicase RecQ Neighboring gene L-homoserine/L-homoserine lactone/L-threonine exporter Neighboring gene lysophospholipase L2

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Activity of exporters of Escherichia coli in Corynebacterium glutamicum, and their use to increase L-threonine production. Diesveld R, et al. J Mol Microbiol Biotechnol, 2009. PMID 18594129
    2. The novel transmembrane Escherichia coli proteins involved in the amino acid efflux. Zakataeva NP, et al. FEBS Lett, 1999 Jun 11. PMID 10386596
    3. The recQ gene of Escherichia coli K12: primary structure and evidence for SOS regulation. Irino N, et al. Mol Gen Genet, 1986 Nov. PMID 3027506
    4. [Expression of the genes encoding RhtB family proteins depends on global regulator Lrp]. Kutukova EA, et al. Mol Biol (Mosk), 2005 May-Jun. PMID 15981566
    5. Analysis of the Escherichia coli genome: DNA sequence of the region from 84.5 to 86.5 minutes. Daniels DL, et al. Science, 1992 Aug 7. PMID 1379743

    See all (15) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables amino acid transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables threonine efflux transmembrane transporter activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables threonine efflux transmembrane transporter activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in amino acid transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in amino acid transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in amino acid transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within threonine transport IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within threonine transport IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in plasma membrane ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    located_in plasma membrane RCA
    inferred from Reviewed Computational Analysis
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    L-threonine exporter

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      4007757..4008377
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. YP_026264.1 L-threonine exporter [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for YP_026264.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A8E0FLC5, A0AAN4AG64, A0AAN4NPU0
      Conserved Domains (1) summary
      PRK10229
      Location:1 → 206
      PRK10229; threonine efflux system; Provisional
    Nucleotide Protein
    Heading Accession and Version

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