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    Il17re interleukin 17 receptor E [ Rattus norvegicus (Norway rat) ]

    Gene ID: 362417, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Il17reprovided by RGD
    Official Full Name
    interleukin 17 receptor Eprovided by RGD
    Primary source
    RGD:735148
    See related
    EnsemblRapid:ENSRNOG00000009204 AllianceGenome:RGD:735148
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable interleukin-17 receptor activity. Predicted to be involved in cytokine-mediated signaling pathway and inflammatory response. Predicted to be located in plasma membrane. Orthologous to human IL17RE (interleukin 17 receptor E). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Lung (RPKM 54.8), Uterus (RPKM 37.2) and 8 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Il17re in Genome Data Viewer
    Location:
    4q42
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 4 NC_086022.1 (148160384..148173830)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 4 NC_051339.1 (146604547..146618206)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 4 NC_005103.4 (145413157..145426608)

    Chromosome 4 - NC_086022.1Genomic Context describing neighboring genes Neighboring gene apolipoprotein O, pseudogene 2 Neighboring gene U2 spliceosomal RNA Neighboring gene jagunal homolog 1 Neighboring gene interleukin 17 receptor C Neighboring gene cysteine-rich with EGF-like domains 1 Neighboring gene proline-rich transmembrane protein 3

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC93201

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables interleukin-17 receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables interleukin-17 receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in cytokine-mediated signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in inflammatory response IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    interleukin-17 receptor E
    Names
    IL-17 receptor E
    IL-17RE

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001004091.1 → NP_001004091.1  interleukin-17 receptor E precursor

      See identical proteins and their annotated locations for NP_001004091.1

      Status: PROVISIONAL

      Source sequence(s)
      BC078742
      UniProtKB/Swiss-Prot
      Q6AZ51, Q6P7B8
      UniProtKB/TrEMBL
      A0A8L2QQI4
      Related
      ENSRNOP00000085698.2, ENSRNOT00000119312.2
      Conserved Domains (2) summary
      pfam08357
      Location:448 → 570
      SEFIR; SEFIR domain
      pfam15037
      Location:38 → 408
      IL17_R_N; Interleukin-17 receptor extracellular region

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086022.1 Reference GRCr8

      Range
      148160384..148173830
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017592700.3 → XP_017448189.1  interleukin-17 receptor E isoform X1

      UniProtKB/Swiss-Prot
      Q6AZ51, Q6P7B8
      UniProtKB/TrEMBL
      A0A8L2QQI4
      Conserved Domains (2) summary
      pfam08357
      Location:448 → 570
      SEFIR; SEFIR domain
      pfam15037
      Location:38 → 408
      IL17_R_N; Interleukin-17 receptor extracellular region
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q6AZ51.1 GenPept UniProtKB/Swiss-Prot:Q6AZ51

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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