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    Sorbs1 sorbin and SH3 domain containing 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 686098, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Sorbs1provided by RGD
    Official Full Name
    sorbin and SH3 domain containing 1provided by RGD
    Primary source
    RGD:1586598
    See related
    EnsemblRapid:ENSRNOG00000015658 AllianceGenome:RGD:1586598
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    CAP; SH3P12
    Summary
    Enables insulin receptor binding activity and ubiquitin protein ligase binding activity. Involved in several processes, including response to L-glutamate; response to activity; and response to insulin. Part of insulin receptor complex. Human ortholog(s) of this gene implicated in obesity and type 2 diabetes mellitus. Orthologous to human SORBS1 (sorbin and SH3 domain containing 1). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Heart (RPKM 576.8), Muscle (RPKM 112.2) and 7 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Sorbs1 in Genome Data Viewer
    Location:
    1q54
    Exon count:
    41
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (249057324..249279703, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (239107882..239330276, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (259373921..259502108, complement)

    Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene cytochrome P450, family 2, subfamily c, polypeptide 22 Neighboring gene PDZ and LIM domain 1 Neighboring gene uncharacterized LOC120097534 Neighboring gene uncharacterized LOC134484023 Neighboring gene uncharacterized LOC102555231 Neighboring gene uncharacterized LOC134485237

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Exercise training increases components of the c-Cbl-associated protein/c-Cbl signaling cascade in muscle of obese Zucker rats. Bernard JR, et al. Metabolism, 2008 Jun. PMID 18502271
    2. Bone marrow-specific Cap gene deletion protects against high-fat diet-induced insulin resistance. Lesniewski LA, et al. Nat Med, 2007 Apr. PMID 17351624
    3. Molecular scanning of the human sorbin and SH3-domain-containing-1 (SORBS1) gene: positive association of the T228A polymorphism with obesity and type 2 diabetes. Lin WH, et al. Hum Mol Genet, 2001 Aug 15. PMID 11532984
    4. Activation of atypical protein kinase Czeta toward TC10 is regulated by high-fat diet and aerobic exercise in skeletal muscle. Saito M, et al. Metabolism, 2008 Sep. PMID 18702941, Free PMC Article
    5. Regulation of Cbl-associated protein/Cbl pathway in muscle and adipose tissues of two animal models of insulin resistance. Thirone AC, et al. Endocrinology, 2004 Jan. PMID 14525909

    See all (17) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables insulin receptor binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables insulin receptor binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables insulin receptor binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables insulin receptor binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables protein kinase binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables signaling receptor complex adaptor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables signaling receptor complex adaptor activity ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables ubiquitin protein ligase binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables ubiquitin protein ligase binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within acetylcholine receptor signaling pathway ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in cellular response to insulin stimulus ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in focal adhesion assembly ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in focal adhesion assembly ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in insulin receptor signaling pathway ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in insulin receptor signaling pathway ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in positive regulation of D-glucose import ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in positive regulation of D-glucose import ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in positive regulation of glycogen biosynthetic process ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in positive regulation of insulin receptor signaling pathway ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in positive regulation of insulin receptor signaling pathway ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in positive regulation of lipid biosynthetic process ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in positive regulation of protein localization to plasma membrane ISO
    Inferred from Sequence Orthology
    more info
    		  
    acts_upstream_of_or_within regulation of skeletal muscle acetylcholine-gated channel clustering ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in response to L-glutamate IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in response to activity IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in response to insulin IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in response to lipid IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in response to starvation IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in stress fiber assembly ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in stress fiber assembly ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    located_in adherens junction ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in adherens junction ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    located_in anchoring junction IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cell-substrate junction ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in cell-substrate junction ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    located_in centrosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in centrosome ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in cytoskeleton ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
    		  
    part_of flotillin complex ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in focal adhesion IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in focal adhesion ISO
    Inferred from Sequence Orthology
    more info
    		  
    part_of insulin receptor complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in membrane ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in membrane raft ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in membrane raft ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    located_in nuclear matrix ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in nucleus ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in stress fiber ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in stress fiber ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    located_in synapse ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    sorbin and SH3 domain-containing protein 1
    Names
    Cbl associated protein
    ponsin

    NCBI Reference Sequences (RefSeq)

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    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001421361.1 → NP_001408290.1  sorbin and SH3 domain-containing protein 1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000001
      Related
      ENSRNOP00000108753.1, ENSRNOT00000162558.1

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086019.1 Reference GRCr8

      Range
      249057324..249279703 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063273987.1 → XP_063130057.1  sorbin and SH3 domain-containing protein 1 isoform X4

    2. XM_063273958.1 → XP_063130028.1  sorbin and SH3 domain-containing protein 1 isoform X1

    3. XM_063273968.1 → XP_063130038.1  sorbin and SH3 domain-containing protein 1 isoform X4

    4. XM_063273962.1 → XP_063130032.1  sorbin and SH3 domain-containing protein 1 isoform X2

    5. XM_063273977.1 → XP_063130047.1  sorbin and SH3 domain-containing protein 1 isoform X4

    6. XM_063273964.1 → XP_063130034.1  sorbin and SH3 domain-containing protein 1 isoform X2

    7. XM_063273954.1 → XP_063130024.1  sorbin and SH3 domain-containing protein 1 isoform X1

    8. XM_063273944.1 → XP_063130014.1  sorbin and SH3 domain-containing protein 1 isoform X1

    9. XM_063273951.1 → XP_063130021.1  sorbin and SH3 domain-containing protein 1 isoform X1

    10. XM_039095037.2 → XP_038950965.1  sorbin and SH3 domain-containing protein 1 isoform X3

      Conserved Domains (4) summary
      cd11916
      Location:1987 → 2045
      SH3_Sorbs1_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11919
      Location:1557 → 1611
      SH3_Sorbs1_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11922
      Location:1631 → 1688
      SH3_Sorbs1_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cl02617
      Location:643 → 683
      Sorb; Sorbin homologous domain

    11. XM_063273997.1 → XP_063130067.1  sorbin and SH3 domain-containing protein 1 isoform X9

    12. XM_063273996.1 → XP_063130066.1  sorbin and SH3 domain-containing protein 1 isoform X8

    13. XM_063274002.1 → XP_063130072.1  sorbin and SH3 domain-containing protein 1 isoform X10

    14. XM_063273992.1 → XP_063130062.1  sorbin and SH3 domain-containing protein 1 isoform X6

    15. XM_063274018.1 → XP_063130088.1  sorbin and SH3 domain-containing protein 1 isoform X12

    16. XM_063273994.1 → XP_063130064.1  sorbin and SH3 domain-containing protein 1 isoform X7

    17. XM_063274047.1 → XP_063130117.1  sorbin and SH3 domain-containing protein 1 isoform X17

    18. XM_063274026.1 → XP_063130096.1  sorbin and SH3 domain-containing protein 1 isoform X13

    19. XM_063274011.1 → XP_063130081.1  sorbin and SH3 domain-containing protein 1 isoform X11

    20. XM_063274053.1 → XP_063130123.1  sorbin and SH3 domain-containing protein 1 isoform X18

    21. XM_063274030.1 → XP_063130100.1  sorbin and SH3 domain-containing protein 1 isoform X14

    22. XM_063274034.1 → XP_063130104.1  sorbin and SH3 domain-containing protein 1 isoform X15

    23. XM_063274037.1 → XP_063130107.1  sorbin and SH3 domain-containing protein 1 isoform X16

    24. XM_063274059.1 → XP_063130129.1  sorbin and SH3 domain-containing protein 1 isoform X19

    25. XM_063274072.1 → XP_063130142.1  sorbin and SH3 domain-containing protein 1 isoform X23

      UniProtKB/TrEMBL
      F1M866

    26. XM_063274069.1 → XP_063130139.1  sorbin and SH3 domain-containing protein 1 isoform X22

      UniProtKB/TrEMBL
      F1M866
      Related
      ENSRNOP00000021225.6, ENSRNOT00000021226.7

    27. XM_063274112.1 → XP_063130182.1  sorbin and SH3 domain-containing protein 1 isoform X34

      UniProtKB/TrEMBL
      F1M866

    28. XM_063274095.1 → XP_063130165.1  sorbin and SH3 domain-containing protein 1 isoform X29

      UniProtKB/TrEMBL
      F1M866

    29. XM_063274063.1 → XP_063130133.1  sorbin and SH3 domain-containing protein 1 isoform X20

      UniProtKB/TrEMBL
      F1M866

    30. XM_039095225.2 → XP_038951153.1  sorbin and SH3 domain-containing protein 1 isoform X43

      UniProtKB/TrEMBL
      F1M866
      Conserved Domains (4) summary
      cd11916
      Location:1217 → 1275
      SH3_Sorbs1_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11919
      Location:1038 → 1092
      SH3_Sorbs1_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11922
      Location:1112 → 1169
      SH3_Sorbs1_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cl02617
      Location:613 → 653
      Sorb; Sorbin homologous domain

    31. XM_039095212.2 → XP_038951140.1  sorbin and SH3 domain-containing protein 1 isoform X37

      UniProtKB/TrEMBL
      A0A8I6ASS7
      Related
      ENSRNOP00000021114.6, ENSRNOT00000021114.10
      Conserved Domains (5) summary
      cd11916
      Location:1256 → 1314
      SH3_Sorbs1_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11919
      Location:826 → 880
      SH3_Sorbs1_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11922
      Location:900 → 957
      SH3_Sorbs1_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      PHA03307
      Location:15 → 399
      PHA03307; transcriptional regulator ICP4; Provisional
      cl02617
      Location:401 → 441
      Sorb; Sorbin homologous domain

    32. XM_063274119.1 → XP_063130189.1  sorbin and SH3 domain-containing protein 1 isoform X36

      UniProtKB/TrEMBL
      A0A8I6ASS7

    33. XM_063274100.1 → XP_063130170.1  sorbin and SH3 domain-containing protein 1 isoform X31

      UniProtKB/TrEMBL
      F1M866

    34. XM_063274089.1 → XP_063130159.1  sorbin and SH3 domain-containing protein 1 isoform X27

      UniProtKB/TrEMBL
      F1M866

    35. XM_063274083.1 → XP_063130153.1  sorbin and SH3 domain-containing protein 1 isoform X25

      UniProtKB/TrEMBL
      F1M866

    36. XM_039095140.2 → XP_038951068.1  sorbin and SH3 domain-containing protein 1 isoform X21

      UniProtKB/TrEMBL
      F1M866
      Conserved Domains (4) summary
      cd11916
      Location:1247 → 1305
      SH3_Sorbs1_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11919
      Location:1068 → 1122
      SH3_Sorbs1_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11922
      Location:1142 → 1199
      SH3_Sorbs1_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cl02617
      Location:643 → 683
      Sorb; Sorbin homologous domain

    37. XM_063274125.1 → XP_063130195.1  sorbin and SH3 domain-containing protein 1 isoform X38

      UniProtKB/TrEMBL
      A0A8I6ASS7
      Related
      ENSRNOP00000097497.2, ENSRNOT00000100551.2

    38. XM_063274118.1 → XP_063130188.1  sorbin and SH3 domain-containing protein 1 isoform X35

      UniProtKB/TrEMBL
      F1M866

    39. XM_039095158.2 → XP_038951086.1  sorbin and SH3 domain-containing protein 1 isoform X30

      UniProtKB/TrEMBL
      F1M866
      Conserved Domains (4) summary
      smart00459
      Location:639 → 684
      Sorb; Sorbin homologous domain
      cd11916
      Location:1187 → 1245
      SH3_Sorbs1_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11919
      Location:988 → 1042
      SH3_Sorbs1_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11922
      Location:1062 → 1119
      SH3_Sorbs1_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin

    40. XM_039095147.2 → XP_038951075.1  sorbin and SH3 domain-containing protein 1 isoform X24

      UniProtKB/TrEMBL
      F1M866
      Conserved Domains (4) summary
      cd11916
      Location:1226 → 1284
      SH3_Sorbs1_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11919
      Location:1047 → 1101
      SH3_Sorbs1_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11922
      Location:1121 → 1178
      SH3_Sorbs1_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cl02617
      Location:643 → 683
      Sorb; Sorbin homologous domain

    41. XM_039095156.2 → XP_038951084.1  sorbin and SH3 domain-containing protein 1 isoform X28

      UniProtKB/TrEMBL
      F1M866
      Conserved Domains (4) summary
      cd11916
      Location:1191 → 1249
      SH3_Sorbs1_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11919
      Location:1012 → 1066
      SH3_Sorbs1_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11922
      Location:1086 → 1143
      SH3_Sorbs1_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cl02617
      Location:643 → 683
      Sorb; Sorbin homologous domain

    42. XM_039095228.2 → XP_038951156.1  sorbin and SH3 domain-containing protein 1 isoform X44

      UniProtKB/TrEMBL
      F1M866
      Conserved Domains (4) summary
      cd11916
      Location:1182 → 1240
      SH3_Sorbs1_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11919
      Location:1003 → 1057
      SH3_Sorbs1_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11922
      Location:1077 → 1134
      SH3_Sorbs1_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cl02617
      Location:634 → 674
      Sorb; Sorbin homologous domain

    43. XM_039095216.2 → XP_038951144.1  sorbin and SH3 domain-containing protein 1 isoform X39

      UniProtKB/TrEMBL
      A0A8I6ASS7
      Conserved Domains (5) summary
      smart00459
      Location:397 → 442
      Sorb; Sorbin homologous domain
      cd11916
      Location:1230 → 1288
      SH3_Sorbs1_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11919
      Location:780 → 834
      SH3_Sorbs1_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11922
      Location:854 → 911
      SH3_Sorbs1_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      PHA03307
      Location:15 → 399
      PHA03307; transcriptional regulator ICP4; Provisional

    44. XM_039095161.2 → XP_038951089.1  sorbin and SH3 domain-containing protein 1 isoform X32

      UniProtKB/TrEMBL
      F1M866
      Conserved Domains (4) summary
      smart00459
      Location:639 → 684
      Sorb; Sorbin homologous domain
      cd11916
      Location:1179 → 1237
      SH3_Sorbs1_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11919
      Location:1000 → 1054
      SH3_Sorbs1_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11922
      Location:1074 → 1131
      SH3_Sorbs1_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin

    45. XM_039095154.2 → XP_038951082.1  sorbin and SH3 domain-containing protein 1 isoform X26

      UniProtKB/TrEMBL
      F1M866
      Conserved Domains (4) summary
      smart00459
      Location:639 → 684
      Sorb; Sorbin homologous domain
      cd11916
      Location:1201 → 1259
      SH3_Sorbs1_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11919
      Location:1022 → 1076
      SH3_Sorbs1_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11922
      Location:1096 → 1153
      SH3_Sorbs1_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin

    46. XM_039095169.2 → XP_038951097.1  sorbin and SH3 domain-containing protein 1 isoform X33

      UniProtKB/TrEMBL
      F1M866
      Conserved Domains (4) summary
      cd11916
      Location:1170 → 1228
      SH3_Sorbs1_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11919
      Location:991 → 1045
      SH3_Sorbs1_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11922
      Location:1065 → 1122
      SH3_Sorbs1_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cl02617
      Location:643 → 683
      Sorb; Sorbin homologous domain

    47. XM_063274132.1 → XP_063130202.1  sorbin and SH3 domain-containing protein 1 isoform X40

      UniProtKB/TrEMBL
      F1M866

    48. XM_063274133.1 → XP_063130203.1  sorbin and SH3 domain-containing protein 1 isoform X42

    49. XM_039095220.2 → XP_038951148.1  sorbin and SH3 domain-containing protein 1 isoform X41

      Conserved Domains (4) summary
      cd11916
      Location:975 → 1033
      SH3_Sorbs1_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11919
      Location:796 → 850
      SH3_Sorbs1_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11922
      Location:870 → 927
      SH3_Sorbs1_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cl02617
      Location:392 → 432
      Sorb; Sorbin homologous domain

    50. XM_063273991.1 → XP_063130061.1  sorbin and SH3 domain-containing protein 1 isoform X5

    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P84109.1 GenPept UniProtKB/Swiss-Prot:P84109

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