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    Zfp62 zinc finger protein 62 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 497894, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Zfp62provided by RGD
    Official Full Name
    zinc finger protein 62provided by RGD
    Primary source
    RGD:1560191
    See related
    AllianceGenome:RGD:1560191
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1560191
    Summary
    Predicted to be involved in positive regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Orthologous to human ZFP62 (ZFP62 zinc finger protein). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Thymus (RPKM 109.8), Spleen (RPKM 87.9) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Zfp62 in Genome Data Viewer
    Location:
    10q21
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (34019367..34040564)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (33522618..33539446)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (34477108..34493941)

    Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC120095085 Neighboring gene olfactory receptor family 2 subfamily M member 13 Neighboring gene butyrophilin-like 9 Neighboring gene uncharacterized LOC134480779 Neighboring gene alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase Neighboring gene olfactory receptor family 2 subfamily Y member 1G

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables DNA-binding transcription activator activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in positive regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    zinc finger protein 62 homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086028.1 Reference GRCr8

      Range
      34019367..34040564
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039087164.2 → XP_038943092.1  zinc finger protein 62 homolog isoform X1

      UniProtKB/TrEMBL
      A0A0G2K5I8
      Conserved Domains (3) summary
      COG5048
      Location:447 → 860
      COG5048; FOG: Zn-finger [General function prediction only]
      COG5189
      Location:389 → 468
      SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
      sd00017
      Location:227 → 247
      ZF_C2H2; C2H2 Zn finger [structural motif]

    2. XM_006246188.5 → XP_006246250.1  zinc finger protein 62 homolog isoform X1

      See identical proteins and their annotated locations for XP_006246250.1

      UniProtKB/TrEMBL
      A0A0G2K5I8
      Conserved Domains (3) summary
      COG5048
      Location:447 → 860
      COG5048; FOG: Zn-finger [General function prediction only]
      COG5189
      Location:389 → 468
      SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
      sd00017
      Location:227 → 247
      ZF_C2H2; C2H2 Zn finger [structural motif]

    3. XM_006246189.5 → XP_006246251.1  zinc finger protein 62 homolog isoform X2

      See identical proteins and their annotated locations for XP_006246251.1

      UniProtKB/TrEMBL
      A0A0G2K5I8
      Conserved Domains (3) summary
      COG5048
      Location:447 → 860
      COG5048; FOG: Zn-finger [General function prediction only]
      COG5189
      Location:389 → 468
      SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
      sd00017
      Location:227 → 247
      ZF_C2H2; C2H2 Zn finger [structural motif]

    4. XM_039087165.1 → XP_038943093.1  zinc finger protein 62 homolog isoform X1

      UniProtKB/TrEMBL
      A0A0G2K5I8
      Conserved Domains (3) summary
      COG5048
      Location:447 → 860
      COG5048; FOG: Zn-finger [General function prediction only]
      COG5189
      Location:389 → 468
      SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
      sd00017
      Location:227 → 247
      ZF_C2H2; C2H2 Zn finger [structural motif]

    5. XM_063270096.1 → XP_063126166.1  zinc finger protein 62 homolog isoform X1

      UniProtKB/TrEMBL
      A0A0G2K5I8
    Nucleotide Protein Strain
    Heading Accession and Version

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