These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

1. NM_001107152.2 → NP_001100622.2  DNA polymerase epsilon catalytic subunit A

   Status: VALIDATED

   Source sequence(s)

   JAXUCZ010000012

   UniProtKB/TrEMBL

   D3Z8X4

   Related

   ENSRNOP00000058920.1, ENSRNOT00000067453.5

   Conserved Domains (5) summary

   cd05779
   Location:268 → 471

   DNA_polB_epsilon_exo; DEDDy 3'-5' exonuclease domain of eukaryotic DNA polymerase epsilon, a family-B DNA polymerase

   cd05535
   Location:531 → 1153

   POLBc_epsilon; DNA polymerase type-B epsilon subfamily catalytic domain. Three DNA-dependent DNA polymerases type B (alpha, delta, and epsilon) have been identified as essential for nuclear DNA replication in eukaryotes. DNA polymerase (Pol) epsilon has been proposed ...

   COG0417
   Location:99 → 1165

   PolB; DNA polymerase elongation subunit (family B) [Replication, recombination and repair]

   pfam08490
   Location:1528 → 1924

   DUF1744; Domain of unknown function (DUF1744)

   cl00013
   Location:125 → 231

   Lyase_I_like; Lyase class I_like superfamily: contains the lyase class I family, histidine ammonia-lyase and phenylalanine ammonia-lyase, which catalyze similar beta-elimination reactions

The following sections contain reference sequences that belong to a specific genome build. Explain

This section includes genomic Reference Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate assemblies. Model RNAs and proteins are also reported here.

Reference GRCr8

Genomic

1. NC_086030.1 Reference GRCr8

   Range

   52005155..52053761 complement

   Download

   GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

1. XM_063271396.1 → XP_063127466.1  DNA polymerase epsilon catalytic subunit A isoform X3

2. XM_039089516.2 → XP_038945444.1  DNA polymerase epsilon catalytic subunit A isoform X1

   Conserved Domains (3) summary

   cd05779
   Location:268 → 471

   DNA_polB_epsilon_exo; DEDDy 3'-5' exonuclease domain of eukaryotic DNA polymerase epsilon, a family-B DNA polymerase

   cd05535
   Location:531 → 1153

   POLBc_epsilon; DNA polymerase type-B epsilon subfamily catalytic domain. Three DNA-dependent DNA polymerases type B (alpha, delta, and epsilon) have been identified as essential for nuclear DNA replication in eukaryotes. DNA polymerase (Pol) epsilon has been proposed ...

   pfam08490
   Location:1525 → 1792

   DUF1744; Domain of unknown function (DUF1744)

3. XM_063271395.1 → XP_063127465.1  DNA polymerase epsilon catalytic subunit A isoform X2

4. XM_039089517.2 → XP_038945445.1  DNA polymerase epsilon catalytic subunit A isoform X4

   Conserved Domains (3) summary

   cd05779
   Location:268 → 471

   DNA_polB_epsilon_exo; DEDDy 3'-5' exonuclease domain of eukaryotic DNA polymerase epsilon, a family-B DNA polymerase

   cd05535
   Location:531 → 1153

   POLBc_epsilon; DNA polymerase type-B epsilon subfamily catalytic domain. Three DNA-dependent DNA polymerases type B (alpha, delta, and epsilon) have been identified as essential for nuclear DNA replication in eukaryotes. DNA polymerase (Pol) epsilon has been proposed ...

   pfam08490
   Location:1525 → 1723

   DUF1744; Domain of unknown function (DUF1744)

RNA

1. XR_005491633.2 RNA Sequence

2. XR_005491635.2 RNA Sequence

3. XR_005491634.2 RNA Sequence

4. XR_010056397.1 RNA Sequence

5. XR_005491637.2 RNA Sequence

6. XR_005491639.2 RNA Sequence

7. XR_010056398.1 RNA Sequence

8. XR_005491638.2 RNA Sequence