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    Col23a1 collagen type XXIII alpha 1 chain [ Rattus norvegicus (Norway rat) ]

    Gene ID: 353303, updated on 9-Dec-2024

    Summary

    Symbol
    Col23a1provided by RGD
    Full Name
    collagen type XXIII alpha 1 chainprovided by RGD
    Primary source
    RGD:727898
    See related
    EnsemblRapid:ENSRNOG00000003349 AllianceGenome:RGD:727898
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Enables heparin binding activity and identical protein binding activity. Predicted to be involved in extracellular matrix organization. Located in cell surface and extracellular space. Orthologous to human COL23A1 (collagen type XXIII alpha 1 chain). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Adrenal (RPKM 58.8), Lung (RPKM 55.5) and 8 other tissues See more
    Orthologs
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    Genomic context

    See Col23a1 in Genome Data Viewer
    Location:
    10q22
    Exon count:
    29
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (36050327..36337279)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (35549090..35839152)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (34846618..34934991)

    Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene putative uncharacterized protein MSANTD5 Neighboring gene Myb/SANT DNA binding domain containing 5 Neighboring gene CDC-like kinase 4 Neighboring gene uncharacterized LOC120095095 Neighboring gene uncharacterized LOC134480786 Neighboring gene transfer RNA alanine (anticodon AGC) Neighboring gene 5-phosphohydroxy-L-lysine phospho-lyase Neighboring gene heterogeneous nuclear ribonucleoprotein A/B

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Pathways from PubChem

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables extracellular matrix structural constituent conferring tensile strength IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables heparin binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables identical protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in extracellular matrix organization IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    located_in cell surface IDA
    Inferred from Direct Assay
    more info
    PubMed 
    part_of collagen trimer IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in collagen-containing extracellular matrix IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in extracellular space IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in extracellular space IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    collagen alpha-1(XXIII) chain
    Names
    alpha 1 type XXIII collagen
    collagen XXIII
    collagen alpha-1(XXIII) chain-like
    collagen, type XXIII, alpha 1
    procollagen, type XXIII, alpha 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_181636.2NP_853667.1  collagen alpha-1(XXIII) chain

      See identical proteins and their annotated locations for NP_853667.1

      Status: PROVISIONAL

      Source sequence(s)
      AY158896
      UniProtKB/Swiss-Prot
      Q810Y4
      UniProtKB/TrEMBL
      D3ZFT7
      Related
      ENSRNOP00000062298.2, ENSRNOT00000064078.3
      Conserved Domains (1) summary
      pfam01391
      Location:455512
      Collagen; Collagen triple helix repeat (20 copies)

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086028.1 Reference GRCr8

      Range
      36050327..36337279
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)