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    wbpI UDP-2,3-diacetamido-2,3-dideoxy-D-glucuronate 2-epimeras [ Pseudomonas aeruginosa PAO1 ]

    Gene ID: 882693, updated on 11-Sep-2024

    Summary

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    Gene symbol
    wbpI
    Gene description
    UDP-2,3-diacetamido-2,3-dideoxy-D-glucuronate 2-epimeras
    Locus tag
    PA3148
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Pseudomonas aeruginosa PAO1 (strain: PAO1)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales; Pseudomonadaceae; Pseudomonas
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    Genomic context

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    Sequence:
    NC_002516.2 (3531751..3532815, complement)

    NC_002516.2Genomic Context describing neighboring genes Neighboring gene NAD-dependent epimerase/dehydratase Neighboring gene glycosyl transferase WbpJ Neighboring gene glycosyltransferase WbpH Neighboring gene LPS biosynthesis protein WbpG Neighboring gene imidazole glycerol phosphate synthase subunit HisF Neighboring gene imidazole glycerol phosphate synthase subunit HisH

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_002516.2

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Identification and biochemical characterization of two novel UDP-2,3-diacetamido-2,3-dideoxy-alpha-D-glucuronic acid 2-epimerases from respiratory pathogens. Westman EL, et al. Biochem J, 2007 Jul 1. PMID 17346239, Free PMC Article
    2. Pseudomonas aeruginosa B-band lipopolysaccharide genes wbpA and wbpI and their Escherichia coli homologues wecC and wecB are not functionally interchangeable. Burrows LL, et al. FEMS Microbiol Lett, 2000 Aug 15. PMID 10930727
    3. Pseudomonas Genome Database: facilitating user-friendly, comprehensive comparisons of microbial genomes. Winsor GL, et al. Nucleic Acids Res, 2009 Jan. PMID 18978025, Free PMC Article
    4. Defining the Pseudomonas aeruginosa SOS response and its role in the global response to the antibiotic ciprofloxacin. Cirz RT, et al. J Bacteriol, 2006 Oct. PMID 17015649, Free PMC Article
    5. Cystic fibrosis sputum supports growth and cues key aspects of Pseudomonas aeruginosa physiology. Palmer KL, et al. J Bacteriol, 2005 Aug. PMID 16030221, Free PMC Article

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Homology

    Gene Ontology Provided by PseudoCAP

    Function Evidence Code Pubs
    enables UDP-N-acetylglucosamine 2-epimerase activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    enables UDP-glucuronate 4-epimerase activity EXP
    Inferred from Experiment
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within O antigen biosynthetic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within polysaccharide biosynthetic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    UDP-2,3-diacetamido-2,3-dideoxy-D-glucuronate 2-epimeras
    NP_251838.1
    • Product name confidence: class 1: Function experimentally demonstrated in P. aeruginosa

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_002516.2 Reference assembly

      Range
      3531751..3532815 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_251838.1 UDP-2,3-diacetamido-2,3-dideoxy-D-glucuronate 2-epimeras [Pseudomonas aeruginosa PAO1]

      See identical proteins and their annotated locations for NP_251838.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      G3XD61
      Conserved Domains (1) summary
      cd03786
      Location:2 → 352
      GTB_UDP-GlcNAc_2-Epimerase; UDP-N-acetylglucosamine 2-epimerase and similar proteins
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    G3XD61.1

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