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    rpoA DNA-directed RNA polymerase subunit alpha [ Pseudomonas aeruginosa PAO1 ]

    Gene ID: 881813, updated on 11-Sep-2024

    Summary

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    Gene symbol
    rpoA
    Gene description
    DNA-directed RNA polymerase subunit alpha
    Locus tag
    PA4238
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Pseudomonas aeruginosa PAO1 (strain: PAO1)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales; Pseudomonadaceae; Pseudomonas
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    Genomic context

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    Sequence:
    NC_002516.2 (4754423..4755424, complement)

    NC_002516.2Genomic Context describing neighboring genes Neighboring gene catalase Neighboring gene 50S ribosomal protein L17 Neighboring gene 30S ribosomal protein S4 Neighboring gene 30S ribosomal protein S11

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_002516.2

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The Phage-Encoded N-Acetyltransferase Rac Mediates Inactivation of Pseudomonas aeruginosa Transcription by Cleavage of the RNA Polymerase Alpha Subunit. Ceyssens PJ, et al. Viruses, 2020 Sep 2. PMID 32887488, Free PMC Article
    2. Activation defects caused by mutations in Escherichia coli rpoA are promoter specific. Gussin GN, et al. J Bacteriol, 1992 Aug. PMID 1629175, Free PMC Article
    3. Pseudomonas Genome Database: facilitating user-friendly, comprehensive comparisons of microbial genomes. Winsor GL, et al. Nucleic Acids Res, 2009 Jan. PMID 18978025, Free PMC Article
    4. Defining the Pseudomonas aeruginosa SOS response and its role in the global response to the antibiotic ciprofloxacin. Cirz RT, et al. J Bacteriol, 2006 Oct. PMID 17015649, Free PMC Article
    5. Cystic fibrosis sputum supports growth and cues key aspects of Pseudomonas aeruginosa physiology. Palmer KL, et al. J Bacteriol, 2005 Aug. PMID 16030221, Free PMC Article

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. The Phage-Encoded N-Acetyltransferase Rac Mediates Inactivation of Pseudomonas aeruginosa Transcription by Cleavage of the RNA Polymerase Alpha Subunit.
      Title: The Phage-Encoded N-Acetyltransferase Rac Mediates Inactivation of Pseudomonas aeruginosa Transcription by Cleavage of the RNA Polymerase Alpha Subunit.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    Gene Ontology Provided by PseudoCAP

    Process Evidence Code Pubs
    acts_upstream_of_or_within DNA-templated transcription ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    DNA-directed RNA polymerase subunit alpha
    NP_252928.1
    • Product name confidence: class 2 (High similarity to functionally studied protein)

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_002516.2 Reference assembly

      Range
      4754423..4755424 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_252928.1 DNA-directed RNA polymerase subunit alpha [Pseudomonas aeruginosa PAO1]

      See identical proteins and their annotated locations for NP_252928.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O52760
      Conserved Domains (1) summary
      PRK05182
      Location:6 → 315
      PRK05182; DNA-directed RNA polymerase subunit alpha; Provisional
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O52760.2

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