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    Pdss2 Decaprenyl diphosphate synthase subunit 2 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 40323, updated on 27-Dec-2024

    Summary

    Official Symbol
    Pdss2provided by FlyBase
    Official Full Name
    Decaprenyl diphosphate synthase subunit 2provided by FlyBase
    Primary source
    FLYBASE:FBgn0037044
    Locus tag
    Dmel_CG10585
    See related
    AllianceGenome:FB:FBgn0037044
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG10585; Dmel\CG10585
    Summary
    Predicted to enable prenyltransferase activity. Predicted to contribute to all-trans-decaprenyl-diphosphate synthase activity. Predicted to be involved in isoprenoid biosynthetic process and ubiquinone biosynthetic process. Predicted to be part of heterotetrameric polyprenyl diphosphate synthase complex. Predicted to be active in mitochondrion. Is expressed in several structures, including circular trunk visceral muscle primordium; dorsal epidermis primordium; embryonic dorsal epidermis; embryonic head epidermis; and gut section. Used to study congenital heart disease. Human ortholog(s) of this gene implicated in primary coenzyme Q10 deficiency 3. Orthologous to human PDSS2 (decaprenyl diphosphate synthase subunit 2). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See Pdss2 in Genome Data Viewer
    Location:
    78A2-78A2; 3-47 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (21027915..21030141)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (21021015..21023241)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene skuld Neighboring gene antisense RNA:CR45944 Neighboring gene small Cajal body-specific RNA : PsiU6-40 Neighboring gene antisense RNA:CR45801 Neighboring gene uncharacterized protein Neighboring gene RNA polymerase III subunit E Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    contributes_to all-trans-decaprenyl-diphosphate synthase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    enables prenyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in isoprenoid biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in ubiquinone biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    part_of heterotetrameric polyprenyl diphosphate synthase complex ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of polyprenyl diphosphate synthase complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    decaprenyl diphosphate synthase subunit 2
    Names
    CG10585-PA
    CG10585-PB
    COQ1 subunit 2
    Pdss2-PA
    Pdss2-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      21027915..21030141
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_141020.4NP_649277.1  decaprenyl diphosphate synthase subunit 2, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_649277.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VP87
      Related
      FBpp0077945
      Conserved Domains (1) summary
      cl00210
      Location:86441
      Isoprenoid_Biosyn_C1; Isoprenoid Biosynthesis enzymes, Class 1
    2. NM_001300209.1NP_001287138.1  decaprenyl diphosphate synthase subunit 2, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001287138.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VP87
      Conserved Domains (1) summary
      cl00210
      Location:86441
      Isoprenoid_Biosyn_C1; Isoprenoid Biosynthesis enzymes, Class 1