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    Ufsp1 UFM1 specific peptidase 1 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 246489, updated on 17-Dec-2024

    Summary

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    Official Symbol
    Ufsp1provided by FlyBase
    Official Full Name
    UFM1 specific peptidase 1provided by FlyBase
    Primary source
    FLYBASE:FBgn0050157
    Locus tag
    Dmel_CG30157
    See related
    AllianceGenome:FB:FBgn0050157
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG30157; Dmel\CG30157; UfSP1
    Summary
    Predicted to enable deUFMylase activity. Orthologous to human UFSP1 (UFM1 specific peptidase 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Ufsp1 in Genome Data Viewer
    Location:
    42E1-42E1; 2-55 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (6974038..6975133, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (2861543..2862638, complement)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene missing-in-metastasis Neighboring gene Chemosensory protein B 42c Neighboring gene Chemosensory protein B 42a Neighboring gene pickpocket 25 Neighboring gene Cytochrome P450 6u1 Neighboring gene long non-coding RNA:CR44170 Neighboring gene long non-coding RNA:CR44171 Neighboring gene visceral mesodermal armadillo-repeats

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Two novel ubiquitin-fold modifier 1 (Ufm1)-specific proteases, UfSP1 and UfSP2. Kang SH, et al. J Biol Chem, 2007 Feb 23. PMID 17182609
    2. A Drosophila DEG/ENaC channel subunit is required for male response to female pheromones. Lin H, et al. Proc Natl Acad Sci U S A, 2005 Sep 6. PMID 16129837, Free PMC Article
    3. In vivo RNAi screening identifies multiple deubiquitinases required for the maintenance of intestinal homeostasis in Drosophila. Zhao B, et al. Insect Biochem Mol Biol, 2024 Sep. PMID 39067716
    4. Genome features of "Dark-fly", a Drosophila line reared long-term in a dark environment. Izutsu M, et al. PLoS One, 2012. PMID 22432011, Free PMC Article
    5. Identification of GOLPH3 Partners in Drosophila Unveils Potential Novel Roles in Tumorigenesis and Neural Disorders. Sechi S, et al. Cells, 2021 Sep 6. PMID 34571985, Free PMC Article

    See all (23) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables deUFMylase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables deUFMylase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    UFM1 specific peptidase 1
    Names
    CG30157-PA
    CG30157-PB
    Ufsp1-PA
    Ufsp1-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      6974038..6975133 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_165499.2 → NP_724519.1  UFM1 specific peptidase 1, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_724519.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q4V6M7
      UniProtKB/TrEMBL
      A0A0B4LFP9
      Related
      FBpp0085517
      Conserved Domains (1) summary
      pfam07910
      Location:44 → 229
      Peptidase_C78; Peptidase family C78

    2. NM_001299222.1 → NP_001286151.1  UFM1 specific peptidase 1, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001286151.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q4V6M7
      UniProtKB/TrEMBL
      A0A0B4LFP9
      Conserved Domains (1) summary
      pfam07910
      Location:44 → 229
      Peptidase_C78; Peptidase family C78
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A0A0B4LFP9 A0A0B4LFP9
    Q4V6M7.1 Q4V6M7

    Gene LinkOut

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