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    CG1902 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 35993, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG1902provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0033434
    Locus tag
    Dmel_CG1902
    See related
    AllianceGenome:FB:FBgn0033434
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG1902
    Summary
    Predicted to enable lipid transfer activity and phosphatidylinositol bisphosphate binding activity. Predicted to be involved in intermembrane lipid transfer. Predicted to be located in late endosome. Is expressed in adult head and organism. Human ortholog(s) of this gene implicated in familial isolated deficiency of vitamin E. Orthologous to human TTPA (alpha tocopherol transfer protein). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG1902 in Genome Data Viewer
    Location:
    45F6-45F6; 2-61 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (9594045..9605624)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (5481550..5493129)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene closca Neighboring gene uncharacterized protein Neighboring gene Microtubule-associated protein 60 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR44285 Neighboring gene Glutathione S transferase T1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Organization and regulation of sex-specific thioredoxin encoding genes in the genus Drosophila. Svensson MJ, et al. Dev Genes Evol, 2007 Sep. PMID 17701050
    2. Genome-wide identification of alternative splice forms down-regulated by nonsense-mediated mRNA decay in Drosophila. Hansen KD, et al. PLoS Genet, 2009 Jun. PMID 19543372, Free PMC Article
    3. Identification of genes that promote or inhibit olfactory memory formation in Drosophila. Walkinshaw E, et al. Genetics, 2015 Apr. PMID 25644700, Free PMC Article
    4. Putative synaptic genes defined from a Drosophila whole body developmental transcriptome by a machine learning approach. Pazos Obregón F, et al. BMC Genomics, 2015 Sep 15. PMID 26370122, Free PMC Article
    5. Development of a Clickable Probe for Profiling of Protein Glutathionylation in the Central Cellular Metabolism of E. coli and Drosophila. Feng S, et al. Chem Biol, 2015 Nov 19. PMID 26526100

    See all (24) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables lipid transfer activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables phosphatidylinositol bisphosphate binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables phosphatidylinositol bisphosphate binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    involved_in intermembrane lipid transfer ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    located_in late endosome ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG1902-PA
    CG1902-PC

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      9594045..9605624
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_136663.4 → NP_610507.1  uncharacterized protein Dmel_CG1902, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_610507.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q7K1M4
      Related
      FBpp0087614
      Conserved Domains (2) summary
      smart01100
      Location:28 → 69
      CRAL_TRIO_N; CRAL/TRIO, N-terminal domain
      pfam00650
      Location:100 → 248
      CRAL_TRIO; CRAL/TRIO domain

    2. NM_165689.3 → NP_724815.1  uncharacterized protein Dmel_CG1902, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_724815.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q7K1M4
      Related
      FBpp0087615
      Conserved Domains (2) summary
      smart01100
      Location:28 → 69
      CRAL_TRIO_N; CRAL/TRIO, N-terminal domain
      pfam00650
      Location:100 → 248
      CRAL_TRIO; CRAL/TRIO domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q7K1M4 Q7K1M4

    Gene LinkOut

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