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    CG1785 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 31810, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG1785provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0030061
    Locus tag
    Dmel_CG1785
    See related
    AllianceGenome:FB:FBgn0030061
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG1785
    Summary
    Predicted to enable 5S rRNA binding activity. Predicted to be involved in rRNA processing and ribosomal large subunit assembly. Predicted to be located in nucleoplasm. Predicted to be active in nucleolus. Is expressed in several structures, including anterior endoderm; embryonic/larval midgut primordium; gut section; larval somatic muscle cell; and mesoderm. Orthologous to human NOP53 (NOP53 ribosome biogenesis factor). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG1785 in Genome Data Viewer
    Location:
    8A2-8A2; 1-24 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (8714936..8717065)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (8608969..8611098)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR44507 Neighboring gene long non-coding RNA:CR44508 Neighboring gene Hexosaminidase 2 Neighboring gene uncharacterized protein Neighboring gene lethal (1) G0020 Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR43297

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Candidate genetic modifiers of retinitis pigmentosa identified by exploiting natural variation in Drosophila. Chow CY, et al. Hum Mol Genet, 2016 Feb 15. PMID 26662796, Free PMC Article
    2. Joint estimates of quantitative trait locus effect and frequency using synthetic recombinant populations of Drosophila melanogaster. Macdonald SJ, et al. Genetics, 2007 Jun. PMID 17435224, Free PMC Article
    3. Absence of N-terminal acetyltransferase diversification during evolution of eukaryotic organisms. Rathore OS, et al. Sci Rep, 2016 Feb 10. PMID 26861501, Free PMC Article
    4. Drosophila Myc interacts with host cell factor (dHCF) to activate transcription and control growth. Furrer M, et al. J Biol Chem, 2010 Dec 17. PMID 20937797, Free PMC Article
    5. Interactions of drosophila cryptochrome. Ozcelik G, et al. Photochem Photobiol, 2024 Sep-Oct. PMID 38314442

    See all (31) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables 5S rRNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in rRNA processing IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in ribosomal large subunit assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in ribosomal large subunit assembly ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleolus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleolus ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    located_in nucleoplasm ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG1785-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      8714936..8717065
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_132274.3 → NP_572502.1  uncharacterized protein Dmel_CG1785 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_572502.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9W3C2
      Related
      FBpp0071193
      Conserved Domains (1) summary
      pfam07767
      Location:20 → 422
      Nop53; Nop53 (60S ribosomal biogenesis)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9W3C2.1 Q9W3C2

    Gene LinkOut

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