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    CG8509 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 32535, updated on 9-Dec-2024

    Summary

    Official Symbol
    CG8509provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0030696
    Locus tag
    Dmel_CG8509
    See related
    AllianceGenome:FB:FBgn0030696
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG8509
    Summary
    Predicted to enable peptidyl-prolyl cis-trans isomerase activity and protein tyrosine phosphatase activator activity. Predicted to be involved in mitotic spindle organization. Predicted to be part of protein phosphatase type 2A complex. Predicted to be active in cytoplasm and nucleus. Human ortholog(s) of this gene implicated in Parkinson's disease 25. Orthologous to human PTPA (protein phosphatase 2 phosphatase activator). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See CG8509 in Genome Data Viewer
    Location:
    13F1-13F1; 1-52 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (15809555..15810947)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (15703588..15704980)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene Peptidoglycan recognition protein LE Neighboring gene long non-coding RNA:CR44384 Neighboring gene scalloped Neighboring gene Clathrin heavy chain Neighboring gene long non-coding RNA:CR32582

    Genomic regions, transcripts, and products

    General gene information

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables peptidyl-prolyl cis-trans isomerase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables phosphatase activator activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein tyrosine phosphatase activator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in mitotic spindle organization IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of protein phosphatase type 2A complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    uncharacterized protein
    Names
    CG8509-PA
    NP_573079.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      15809555..15810947
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_132851.3NP_573079.1  uncharacterized protein Dmel_CG8509 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_573079.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VXN8
      Related
      FBpp0073913
      Conserved Domains (1) summary
      pfam03095
      Location:27324
      PTPA; Phosphotyrosyl phosphate activator (PTPA) protein