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    CG7987 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 41768, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG7987provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0038244
    Locus tag
    Dmel_CG7987
    See related
    AllianceGenome:FB:FBgn0038244
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    anon-WO0118547.245; Dmel\CG7987
    Summary
    Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in several structures, including anterior endoderm; anterior endoderm anlage; embryonic/larval midgut primordium; gut section; and mesoderm. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG7987 in Genome Data Viewer
    Location:
    88C6-88C6; 3-55 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (14570472..14575887, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (10396194..10401609, complement)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene antisense RNA:CR44095 Neighboring gene uncharacterized protein Neighboring gene Cystatin-like Neighboring gene uncharacterized protein Neighboring gene stumps Neighboring gene long non-coding RNA:CR46153

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Functional relevance of genes predicted to be affected by epigenetic alterations in atypical teratoid/rhabdoid tumors. Tegeder I, et al. J Neurooncol, 2019 Jan. PMID 30446899
    2. Identification of novel Drosophila neural precursor genes using a differential embryonic head cDNA screen. Brody T, et al. Mech Dev, 2002 Apr. PMID 11900973
    3. A large-scale, in vivo transcription factor screen defines bivalent chromatin as a key property of regulatory factors mediating Drosophila wing development. Schertel C, et al. Genome Res, 2015 Apr. PMID 25568052, Free PMC Article
    4. The genetic basis for variation in olfactory behavior in Drosophila melanogaster. Arya GH, et al. Chem Senses, 2015 May. PMID 25687947, Free PMC Article
    5. Phylostratigraphic bias creates spurious patterns of genome evolution. Moyers BA, et al. Mol Biol Evol, 2015 Jan. PMID 25312911, Free PMC Article

    See all (23) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables DNA-binding transcription repressor activity, RNA polymerase II-specific ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in negative regulation of transcription by RNA polymerase II ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG7987-PA
    CG7987-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      14570472..14575887 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_142118.2 → NP_650375.1  uncharacterized protein Dmel_CG7987, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_650375.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q29R10
      Related
      FBpp0082437
      Conserved Domains (6) summary
      COG5048
      Location:326 → 734
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:620 → 640
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00019
      Location:534 → 554
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00020
      Location:709 → 726
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13465
      Location:661 → 685
      zf-H2C2_2; Zinc-finger double domain
      pfam13694
      Location:921 → 1017
      Hph; Sec63/Sec62 complex-interacting family

    2. NM_169587.2 → NP_731922.1  uncharacterized protein Dmel_CG7987, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_731922.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q29R10
      Related
      FBpp0082438
      Conserved Domains (6) summary
      COG5048
      Location:326 → 734
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:620 → 640
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00019
      Location:534 → 554
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00020
      Location:709 → 726
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13465
      Location:661 → 685
      zf-H2C2_2; Zinc-finger double domain
      pfam13694
      Location:921 → 1017
      Hph; Sec63/Sec62 complex-interacting family
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q29R10 Q29R10
    Q8T3L3 Q8T3L3

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