CG9667 uncharacterized protein [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: CG9667provided by FlyBase
Official Full Name: uncharacterized proteinprovided by FlyBase
Primary source: FLYBASE:FBgn0037550
Locus tag: Dmel_CG9667
See related: AllianceGenome:FB:FBgn0037550
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: Dmel\CG9667; ISY1
Summary: Predicted to enable RNA binding activity. Predicted to be involved in generation of catalytic spliceosome for second transesterification step and mRNA 3'-splice site recognition. Part of Prp19 complex. Is expressed in several structures, including anterior endoderm; anterior endoderm anlage; central brain primordium; embryonic/larval midgut primordium; and ganglia. Orthologous to human ISY1 (ISY1 splicing factor homolog) and ISY1-RAB43 (ISY1-RAB43 readthrough). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	3R	NT_033777.3 (8125290..8126357, complement)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	3R	NT_033777.2 (3951012..3952079, complement)

Chromosome 3R - NT_033777.3 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables RNA binding	ISS Inferred from Sequence or Structural Similarity more info

Process	Evidence Code	Pubs
involved_in generation of catalytic spliceosome for second transesterification step	IBA Inferred from Biological aspect of Ancestor more info
involved_in generation of catalytic spliceosome for second transesterification step	IEA Inferred from Electronic Annotation more info
involved_in mRNA 3'-splice site recognition	IBA Inferred from Biological aspect of Ancestor more info
involved_in mRNA splicing, via spliceosome	IC Inferred by Curator more info	PubMed

Component	Evidence Code	Pubs
part_of Prp19 complex	IBA Inferred from Biological aspect of Ancestor more info
part_of Prp19 complex	IDA Inferred from Direct Assay more info	PubMed
part_of catalytic step 2 spliceosome	HDA more info	PubMed
part_of catalytic step 2 spliceosome	IBA Inferred from Biological aspect of Ancestor more info
part_of post-mRNA release spliceosomal complex	IBA Inferred from Biological aspect of Ancestor more info
part_of post-spliceosomal complex	IBA Inferred from Biological aspect of Ancestor more info
part_of precatalytic spliceosome	HDA more info	PubMed

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The following sections contain reference sequences that belong to a specific genome build. Explain