U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    Wsck wsck [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 318600, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    Wsckprovided by FlyBase
    Official Full Name
    wsckprovided by FlyBase
    Primary source
    FLYBASE:FBgn0046685
    Locus tag
    Dmel_CG31127
    See related
    AllianceGenome:FB:FBgn0046685
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BcDNA:LD25626; BcDNA:SD05152; CG31127; Dmel\CG31127; WSCK
    Summary
    Predicted to enable ATP binding activity. Predicted to be active in plasma membrane. Is expressed in adult head. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See Wsck in Genome Data Viewer
    Location:
    96A13-96A13; 3-85 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (24627066..24630075, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (20452788..20455797, complement)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene molting defective Neighboring gene long non-coding RNA:CR46095 Neighboring gene Syntaxin 18 Neighboring gene atlastin Neighboring gene Metallothionein F Neighboring gene puffyeye

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Loss of spastic paraplegia gene atlastin induces age-dependent death of dopaminergic neurons in Drosophila. Lee Y, et al. Neurobiol Aging, 2008 Jan. PMID 17030474
    2. Drosophila Atlastin regulates the stability of muscle microtubules and is required for synapse development. Lee M, et al. Dev Biol, 2009 Jun 15. PMID 19341724
    3. Segmental duplication, microinversion, and gene loss associated with a complex inversion breakpoint region in Drosophila. Calvete O, et al. Mol Biol Evol, 2012 Jul. PMID 22328714, Free PMC Article
    4. Classification of nonenzymatic homologues of protein kinases. Anamika K, et al. Comp Funct Genomics, 2009. PMID 19809514, Free PMC Article
    5. The ligand Sas and its receptor PTP10D drive tumour-suppressive cell competition. Yamamoto M, et al. Nature, 2017 Feb 9. PMID 28092921

    See all (28) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    NOT enables protein kinase activity IKR
    Inferred from Key Residues
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    wsck
    Names
    CG31127-PA
    Wsck-PA

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      24627066..24630075 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_170155.2 → NP_733018.1  wsck [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_733018.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P83097, Q8I0H1, Q95TS7
      Related
      FBpp0084049
      Conserved Domains (4) summary
      smart00219
      Location:493 → 746
      TyrKc; Tyrosine kinase, catalytic domain
      cd00192
      Location:497 → 750
      PTKc; Catalytic domain of Protein Tyrosine Kinases
      pfam00041
      Location:130 → 222
      fn3; Fibronectin type III domain
      pfam01822
      Location:42 → 115
      WSC; WSC domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P83097.2 P83097

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Other Literature Sources
    Molecular Biology Databases
    Research Materials
    Tools
    Miscellaneous