U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    uncharacterized protein [ Saccharomyces cerevisiae S288C ]

    Gene ID: 854908, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Full Name
    uncharacterized protein
    Primary source
    SGD:S000004600
    Locus tag
    YML131W
    See related
    AllianceGenome:SGD:S000004600; FungiDB:YML131W; VEuPathDB:YML131W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Predicted to enable oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor. Located in cytosol. Orthologous to several human genes including PTGR2 (prostaglandin reductase 2). [provided by Alliance of Genome Resources, Dec 2024]
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    Location:
    chromosome: XIII
    Exon count:
    1
    Sequence:
    Chromosome: XIII; NC_001145.3 (10198..11295)

    Chromosome XIII - NC_001145.3Genomic Context describing neighboring genes Neighboring gene Y' element ATP-dependent helicase Neighboring gene Cos3p Neighboring gene ER oxidoreductin Neighboring gene Cox14p

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_001145.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Evaluation of toxicity of the mycotoxin citrinin using yeast ORF DNA microarray and Oligo DNA microarray. Iwahashi H, et al. BMC Genomics, 2007 Apr 5. PMID 17408496, Free PMC Article
    2. Role of Hog1 and Yaf9 in the transcriptional response of Saccharomyces cerevisiae to cesium chloride. Del Vescovo V, et al. Physiol Genomics, 2008 Mar 14. PMID 18198280
    3. Diversity, taxonomy and evolution of medium-chain dehydrogenase/reductase superfamily. Riveros-Rosas H, et al. Eur J Biochem, 2003 Aug. PMID 12899689
    4. Activation of heat shock and antioxidant responses by the natural product celastrol: transcriptional signatures of a thiol-targeted molecule. Trott A, et al. Mol Biol Cell, 2008 Mar. PMID 18199679, Free PMC Article
    5. The Saccharomyces cerevisiae Sko1p transcription factor mediates HOG pathway-dependent osmotic regulation of a set of genes encoding enzymes implicated in protection from oxidative damage. Rep M, et al. Mol Microbiol, 2001 Jun. PMID 11401713

    See all (26) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    enables oxidoreductase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm HDA PubMed 
    located_in cytosol HDA PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    uncharacterized protein
    NP_013575.1
    • hypothetical protein; similar to medium chain dehydrogenase/reductases; expression induced by stresses including osmotic shock, DNA damaging agents, and other chemicals; GFP-fusion protein localizes to the cytoplasm; protein abundance increases in response to DNA replication stress

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001145.3 Reference assembly

      Range
      10198..11295
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001182494.1 → NP_013575.1  TPA: uncharacterized protein YML131W [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_013575.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6W0F4, Q03102, Q6Q5K5
      UniProtKB/TrEMBL
      A6ZLT4, B3LLC9, B5VP00, C7GVB2, C8ZE71, G2WJS6
      Conserved Domains (1) summary
      COG2130
      Location:1 → 363
      CurA; NADPH-dependent curcumin reductase CurA [Secondary metabolites biosynthesis, transport and catabolism, General function prediction only]
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q03102.1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Other Literature Sources
    Molecular Biology Databases
    Research Materials
    Tools