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    frc formyl-CoA transferase [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 946842, updated on 17-Dec-2024

    Summary

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    Official Symbol
    frc
    Official Full Name
    formyl-CoA transferase
    Primary source
    ECOCYC:G7237
    Locus tag
    b2374
    See related
    ASAP:ABE-0007828
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK2370; yfdW
    Summary
    Orthologous to O. formigenes Frc. [More information is available at EcoGene: EG14145]. YfdW (Frc) is a formyl-CoA transferase with sequence and structural similarity to Frc from Oxalobacter formigenes, a strictly anaerobic bacterium found in the mammalian gut . [More information is available at EcoCyc: G7237].
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    Genomic context

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    Sequence:
    NC_000913.3 (2492004..2493254, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene putative transport protein YfdV Neighboring gene oxalyl-CoA decarboxylase Neighboring gene protein YfdX Neighboring gene colanic acid synthesis putative lipoprotein YpdI

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Differential substrate specificity and kinetic behavior of Escherichia coli YfdW and Oxalobacter formigenes formyl coenzyme A transferase. Toyota CG, et al. J Bacteriol, 2008 Apr. PMID 18245280, Free PMC Article
    2. Structure of Escherichia coli YfdW, a type III CoA transferase. Gogos A, et al. Acta Crystallogr D Biol Crystallogr, 2004 Mar. PMID 14993676
    3. Medium-scale structural genomics: strategies for protein expression and crystallization. Vincentelli R, et al. Acc Chem Res, 2003 Mar. PMID 12641473
    4. A medium-throughput crystallization approach. Sulzenbacher G, et al. Acta Crystallogr D Biol Crystallogr, 2002 Dec. PMID 12454472
    5. DNA sequencing and expression of the formyl coenzyme A transferase gene, frc, from Oxalobacter formigenes. Sidhu H, et al. J Bacteriol, 1997 May. PMID 9150242, Free PMC Article

    See all (15) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables CoA-transferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables formyl-CoA transferase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables formyl-CoA transferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within cellular response to acidic pH IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in oxalate catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    formyl-CoA transferase
    NP_416875.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      2492004..2493254 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_416875.1 formyl-CoA transferase [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_416875.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A1D8F583, A0A837B352, A0AAN3MBY8
      Conserved Domains (1) summary
      PRK05398
      Location:1 → 416
      PRK05398; formyl-coenzyme A transferase; Provisional
    Nucleotide Protein
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