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    iap alkaline phosphatase isozyme conversion protein [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 947215, updated on 3-Dec-2024

    Summary

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    Official Symbol
    iap
    Official Full Name
    alkaline phosphatase isozyme conversion protein
    Primary source
    ECOCYC:EG10488
    Locus tag
    b2753
    See related
    ASAP:ABE-0009033
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK2748
    Summary
    First 24 aa are predicted to be a type I signal peptide. [More information is available at EcoGene: EG10488]. Alkaline phosphatase isozyme conversion protein is responsible for the stepwise removal of the two amino-terminal arginines from alkaline phosphatase isozyme 1, creating isozymes 2 and 3 in the process . [More information is available at EcoCyc: EG10488].
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    Genomic context

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    Sequence:
    NC_000913.3 (2876581..2877618)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene adenylyl-sulfate kinase Neighboring gene sulfate adenylyltransferase subunit 1 Neighboring gene sulfate adenylyltransferase subunit 2 Neighboring gene CRISPR-associated endoribonuclease Cas2 Neighboring gene multifunctional nuclease Cas1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Dominance of alkaline phosphatase isozyme gene (IAP+) of Escherichia coli K-12. Nakata A, et al. Biken J, 1980 Mar. PMID 7002151
    2. Factors affecting the formation of alkaline phosphatase isozymes in Escherichia coli K-12. Nakata A, et al. Biken J, 1977 Jun. PMID 337967
    3. Escherichia coli mutants deficient in the production of alkaline phosphatase isozymes. Nakata A, et al. J Bacteriol, 1978 Apr. PMID 348683, Free PMC Article
    4. Alkaline phosphatase isozyme conversion by cell-free extract of Escherichia coli. Nakata A, et al. FEBS Lett, 1984 Oct 1. PMID 6383868
    5. Short palindromic repetitive DNA elements in enterobacteria: a survey. Bachellier S, et al. Res Microbiol, 1999 Nov-Dec. PMID 10673002

    See all (17) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables aminopeptidase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables aminopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables metalloexopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within post-translational protein modification IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in proteolysis IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in outer membrane-bounded periplasmic space IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    alkaline phosphatase isozyme conversion protein

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      2876581..2877618
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_417233.1 alkaline phosphatase isozyme conversion protein [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_417233.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A792HVR0, A0A7A6RRW5
      Conserved Domains (1) summary
      PRK10199
      Location:1 → 345
      PRK10199; alkaline phosphatase isozyme conversion aminopeptidase; Provisional
    Nucleotide Protein
    Heading Accession and Version

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