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    yehY glycine betaine ABC transporter membrane subunit YehY [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 946660, updated on 17-Dec-2024

    Summary

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    Official Symbol
    yehY
    Official Full Name
    glycine betaine ABC transporter membrane subunit YehY
    Primary source
    ECOCYC:EG12011
    Locus tag
    b2130
    See related
    ASAP:ABE-0007038
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK2123
    Summary
    RpoS regulon. [More information is available at EcoGene: EG12011]. YehY is a membrane component of an ABC transporter involved in osmoprotection. [More information is available at EcoCyc: EG12011].
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    Genomic context

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    Sequence:
    NC_000913.3 (2217400..2218557, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene DNA-binding transcriptional activator MlrA Neighboring gene UPF0387 family protein YohO Neighboring gene glycine betaine ABC transporter membrane subunit YehW Neighboring gene glycine betaine ABC transporter ATP binding subunit YehX Neighboring gene glycine betaine ABC transporter periplasmic binding protein OsmF Neighboring gene beta-D-glucoside glucohydrolase, periplasmic

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Osmoregulatory systems of Escherichia coli: identification of betaine-carnitine-choline transporter family member BetU and distributions of betU and trkG among pathogenic and nonpathogenic isolates. Ly A, et al. J Bacteriol, 2004 Jan. PMID 14702297, Free PMC Article
    2. Identification of RpoS (sigma(S))-regulated genes in Salmonella enterica serovar typhimurium. Ibanez-Ruiz M, et al. J Bacteriol, 2000 Oct. PMID 11004173, Free PMC Article
    3. YehZYXW of Escherichia coli Is a Low-Affinity, Non-Osmoregulatory Betaine-Specific ABC Transporter. Lang S, et al. Biochemistry, 2015 Sep 22. PMID 26325238
    4. Getting in or out: early segregation between importers and exporters in the evolution of ATP-binding cassette (ABC) transporters. Saurin W, et al. J Mol Evol, 1999 Jan. PMID 9873074
    5. Interaction network containing conserved and essential protein complexes in Escherichia coli. Butland G, et al. Nature, 2005 Feb 3. PMID 15690043

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in amino acid transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in amino-acid betaine transport NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    involved_in glycine betaine transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within glycine betaine transport IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    part_of ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing RCA
    inferred from Reviewed Computational Analysis
    more info
    		 PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in plasma membrane RCA
    inferred from Reviewed Computational Analysis
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    glycine betaine ABC transporter membrane subunit YehY

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      2217400..2218557 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_416634.1 glycine betaine ABC transporter membrane subunit YehY [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_416634.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A8T5YCV4
      Conserved Domains (1) summary
      COG1174
      Location:150 → 385
      OpuBB; ABC-type proline/glycine betaine transport system, permease component [Amino acid transport and metabolism]
    Nucleotide Protein
    Heading Accession and Version

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