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    CG45263 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 50003, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG45263provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0266801
    Locus tag
    Dmel_CG45263
    See related
    AllianceGenome:FB:FBgn0266801
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    43462; anon-EST:Posey178; BcDNA:AT05815; BcDNA:GH22170; CG11718; CG11729; CG11730; CG11731; CG11733; CG31264; CG31369; CG31462; CG42285; CG42286; CG43462; CT32186; Dmel\CG45263; GH22170; GS3056; MRE1
    Old locus tag
    Dmel_CG11718; Dmel_CG31369; Dmel_CG31462; Dmel_CG42285; Dmel_CG42286; Dmel_CG43462
    Summary
    Predicted to enable cell adhesion molecule binding activity. Predicted to be involved in cell-cell adhesion. Predicted to be active in cell-cell junction and plasma membrane. Is expressed in several structures, including amnioserosa anlage; amnioserosa primordium; dorsal ectoderm; epithelium; and sensory nervous system primordium. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG45263 in Genome Data Viewer
    Location:
    84F15-85A2; 3-48 cM
    Exon count:
    18
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (8364328..8477617, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (4190050..4303339, complement)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene veneno Neighboring gene steamer duck Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR46126 Neighboring gene Odorant-binding protein 85a Neighboring gene long non-coding RNA:CR46125 Neighboring gene Odorant receptor 85b Neighboring gene Odorant receptor 85c

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Drosophila PQBP1 regulates learning acquisition at projection neurons in aversive olfactory conditioning. Tamura T, et al. J Neurosci, 2010 Oct 20. PMID 20962230, Free PMC Article
    2. Classifying Drosophila Olfactory Projection Neuron Subtypes by Single-Cell RNA Sequencing. Li H, et al. Cell, 2017 Nov 16. PMID 29149607, Free PMC Article
    3. Cross-phenotype association tests uncover genes mediating nutrient response in Drosophila. Nelson CS, et al. BMC Genomics, 2016 Nov 4. PMID 27809764, Free PMC Article
    4. Application of the gene search system to screen for longevity genes in Drosophila. Seong KH, et al. Biogerontology, 2001. PMID 11708722
    5. Target genes of Dpp/BMP signaling pathway revealed by transcriptome profiling in the early D.melanogaster embryo. Dominguez C, et al. Gene, 2016 Oct 10. PMID 27397649

    See all (36) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. these findings identify dPQBP1 as a novel gene regulating learning acquisition at projection neurons
      Title: Drosophila PQBP1 regulates learning acquisition at projection neurons in aversive olfactory conditioning.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables cell adhesion molecule binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in cell-cell adhesion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cell-cell junction IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG45263-PB
    CG45263-PC
    CG45263-PD
    CG45263-PE
    CG45263-PF
    CG45263-PG
    mRNA-like ncRNA in embryogenesis 1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      8364328..8477617 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001260059.2 → NP_001246988.1  uncharacterized protein Dmel_CG45263, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001246988.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0B4K609
      Conserved Domains (4) summary
      smart00408
      Location:302 → 357
      IGc2; Immunoglobulin C-2 Type
      smart00410
      Location:478 → 570
      IG_like; Immunoglobulin like
      pfam07679
      Location:53 → 149
      I-set; Immunoglobulin I-set domain
      cl11960
      Location:198 → 281
      Ig; Immunoglobulin domain

    2. NM_001260060.2 → NP_001246989.1  uncharacterized protein Dmel_CG45263, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001246989.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0B4K642
      Conserved Domains (4) summary
      smart00408
      Location:302 → 357
      IGc2; Immunoglobulin C-2 Type
      smart00410
      Location:478 → 570
      IG_like; Immunoglobulin like
      pfam07679
      Location:53 → 149
      I-set; Immunoglobulin I-set domain
      cl11960
      Location:198 → 281
      Ig; Immunoglobulin domain

    3. NM_001316568.1 → NP_001303497.1  uncharacterized protein Dmel_CG45263, isoform F [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A126GUR3, B5X504
      Conserved Domains (4) summary
      smart00408
      Location:302 → 357
      IGc2; Immunoglobulin C-2 Type
      smart00410
      Location:478 → 570
      IG_like; Immunoglobulin like
      pfam07679
      Location:53 → 149
      I-set; Immunoglobulin I-set domain
      cl11960
      Location:198 → 281
      Ig; Immunoglobulin domain

    4. NM_169223.4 → NP_731247.3  uncharacterized protein Dmel_CG45263, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_731247.3

      Status: REVIEWED

      UniProtKB/TrEMBL
      B5X504, Q9VHQ8
      Conserved Domains (4) summary
      smart00408
      Location:302 → 357
      IGc2; Immunoglobulin C-2 Type
      smart00410
      Location:478 → 570
      IG_like; Immunoglobulin like
      pfam07679
      Location:53 → 149
      I-set; Immunoglobulin I-set domain
      cl11960
      Location:198 → 281
      Ig; Immunoglobulin domain

    5. NM_169222.3 → NP_731246.2  uncharacterized protein Dmel_CG45263, isoform E [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_731246.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VHR2
      Conserved Domains (4) summary
      smart00408
      Location:302 → 357
      IGc2; Immunoglobulin C-2 Type
      smart00410
      Location:478 → 570
      IG_like; Immunoglobulin like
      pfam07679
      Location:53 → 149
      I-set; Immunoglobulin I-set domain
      cl11960
      Location:198 → 281
      Ig; Immunoglobulin domain

    6. NM_001316569.1 → NP_001303498.1  uncharacterized protein Dmel_CG45263, isoform G [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A126GUS1, B5X504
      Conserved Domains (4) summary
      smart00408
      Location:302 → 357
      IGc2; Immunoglobulin C-2 Type
      smart00410
      Location:478 → 570
      IG_like; Immunoglobulin like
      pfam07679
      Location:53 → 149
      I-set; Immunoglobulin I-set domain
      cl11960
      Location:198 → 281
      Ig; Immunoglobulin domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A0A0B4K609 A0A0B4K609
    A0A0B4K642 A0A0B4K642
    A0A126GUR3 A0A126GUR3
    A0A126GUS1 A0A126GUS1
    Q8T916 Q8T916
    Q95T48 Q95T48
    Q9N9Z4 Q9N9Z4
    Q9VHQ8 Q9VHQ8
    Q9VHR2 Q9VHR2

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