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    Wscd2 WSC domain containing 2 [ Mus musculus (house mouse) ]

    Gene ID: 320916, updated on 9-Dec-2024

    Summary

    Official Symbol
    Wscd2provided by MGI
    Official Full Name
    WSC domain containing 2provided by MGI
    Primary source
    MGI:MGI:2445030
    See related
    Ensembl:ENSMUSG00000063430 AllianceGenome:MGI:2445030
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Gm450; 4933413A10Rik; C530024P05Rik
    Summary
    Enables sulfotransferase activity. Located in Golgi membrane. Is expressed in inner ear; skeleton; tarsus; and telencephalon mantle layer. Orthologous to human WSCD2 (WSC domain containing 2). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Broad expression in cerebellum adult (RPKM 22.8), colon adult (RPKM 8.6) and 21 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Wscd2 in Genome Data Viewer
    Location:
    5 F; 5 55.55 cM
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (113636976..113727786)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (113489110..113589725)

    Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_14038 Neighboring gene activator of yeast meiotic promoters 1 Neighboring gene STARR-seq mESC enhancer starr_14039 Neighboring gene STARR-seq mESC enhancer starr_14040 Neighboring gene predicted gene, 30812 Neighboring gene STARR-seq mESC enhancer starr_14042 Neighboring gene predicted gene, 52822 Neighboring gene STARR-seq mESC enhancer starr_14044 Neighboring gene STARR-seq mESC enhancer starr_14048 Neighboring gene STARR-seq mESC enhancer starr_14049 Neighboring gene chemerin chemokine-like receptor 1 Neighboring gene predicted gene 15736 Neighboring gene predicted gene, 52823

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (4) 

    General gene information

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    enables sulfotransferase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
     
    Component Evidence Code Pubs
    located_in Golgi membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    is_active_in cellular_component ND
    No biological Data available
    more info
     

    General protein information

    Preferred Names
    sialate:O-sulfotransferase 2
    Names
    WSC domain-containing protein 2

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_177292.3NP_796266.2  sialate:O-sulfotransferase 2

      See identical proteins and their annotated locations for NP_796266.2

      Status: VALIDATED

      Source sequence(s)
      BC096526
      Consensus CDS
      CCDS19550.2
      UniProtKB/Swiss-Prot
      D4PHA7, Q69ZZ2, Q8C7Q3
      Related
      ENSMUSP00000092021.4, ENSMUST00000094452.4
      Conserved Domains (2) summary
      smart00321
      Location:134225
      WSC; present in yeast cell wall integrity and stress response component proteins
      cl21551
      Location:421513
      Sulfotransfer_3; Sulfotransferase family

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000071.7 Reference GRCm39 C57BL/6J

      Range
      113636976..113727786
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017320928.2XP_017176417.1  sialate:O-sulfotransferase 2 isoform X1

      UniProtKB/Swiss-Prot
      D4PHA7, Q69ZZ2, Q8C7Q3
      Conserved Domains (2) summary
      smart00321
      Location:134225
      WSC; present in yeast cell wall integrity and stress response component proteins
      cl21551
      Location:421513
      Sulfotransfer_3; Sulfotransferase family
    2. XM_036165221.1XP_036021114.1  sialate:O-sulfotransferase 2 isoform X3

      Conserved Domains (2) summary
      smart00321
      Location:172
      WSC; present in yeast cell wall integrity and stress response component proteins
      cl21551
      Location:163255
      Sulfotransfer_3; Sulfotransferase family
    3. XM_030254582.2XP_030110442.1  sialate:O-sulfotransferase 2 isoform X2

      Conserved Domains (3) summary
      smart00321
      Location:34128
      WSC; present in yeast cell wall integrity and stress response component proteins
      cl02568
      Location:123
      WSC; WSC domain
      cl21551
      Location:219311
      Sulfotransfer_3; Sulfotransferase family