Rpl27a ribosomal protein L27A [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Rpl27aprovided by RGD
Official Full Name: ribosomal protein L27Aprovided by RGD
Primary source: RGD:1309771
See related: EnsemblRapid:ENSRNOG00000088362 AllianceGenome:RGD:1309771
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to be a structural constituent of ribosome. Predicted to act upstream of or within translation. Part of cytosolic large ribosomal subunit. Orthologous to human RPL27A (ribosomal protein L27a). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in Spleen (RPKM 3458.8), Thymus (RPKM 3017.6) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 1q33

Exon count:: 7

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	1	NC_086019.1 (172971957..172977591)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	1	NC_051336.1 (163539732..163542771)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	1	NC_005100.4 (174132798..174135816)

Chromosome 1 - NC_086019.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

AA900726 (e-PCR)
- UniSTS:248894

MARC_1767-1768:991931306:1 (e-PCR)
- UniSTS:230861

Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables structural constituent of ribosome	IBA Inferred from Biological aspect of Ancestor more info
enables structural constituent of ribosome	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
involved_in biological_process	ND No biological Data available more info
acts_upstream_of_or_within translation	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
located_in cytoplasm	ISO Inferred from Sequence Orthology more info
located_in cytosol	ISO Inferred from Sequence Orthology more info
part_of cytosolic large ribosomal subunit	IBA Inferred from Biological aspect of Ancestor more info
part_of cytosolic large ribosomal subunit	IDA Inferred from Direct Assay more info	PubMed
part_of cytosolic large ribosomal subunit	ISO Inferred from Sequence Orthology more info
located_in cytosolic ribosome	ISO Inferred from Sequence Orthology more info
located_in endoplasmic reticulum	ISO Inferred from Sequence Orthology more info
is_active_in synapse	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: large ribosomal subunit protein uL15

Names: 60S ribosomal protein L27a

NP_001099760.1

EC 3.6.5.3

XP_038962893.1

EC 3.6.5.3

XP_063141882.1

EC 3.6.5.3

XP_063141886.1

EC 3.6.5.3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001106290.1 → NP_001099760.1 large ribosomal subunit protein uL15

See identical proteins and their annotated locations for NP_001099760.1

Status: PROVISIONAL

Source sequence(s)

CH473956

UniProtKB/Swiss-Prot

P18445

UniProtKB/TrEMBL

A6I7W7

Conserved Domains (1) summary

PTZ00160
Location:1 → 148

PTZ00160; 60S ribosomal protein L27a; Provisional

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

NC_086019.1 Reference GRCr8

Range

172971957..172977591

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_063285816.1 → XP_063141886.1 large ribosomal subunit protein uL15 isoform X1

UniProtKB/Swiss-Prot

P18445

UniProtKB/TrEMBL

A6I7W7

Related

ENSRNOP00000104380.1, ENSRNOT00000145523.1
XM_063285812.1 → XP_063141882.1 large ribosomal subunit protein uL15 isoform X1

UniProtKB/Swiss-Prot

P18445

UniProtKB/TrEMBL

A6I7W7
XM_039106965.2 → XP_038962893.1 large ribosomal subunit protein uL15 isoform X2

UniProtKB/TrEMBL

A6I7W9, A6JAD5

Conserved Domains (1) summary

cl12022
Location:1 → 111

Ribosomal_L27A; Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A