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    Osbpl9 oxysterol binding protein-like 9 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 298369, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Osbpl9provided by RGD
    Official Full Name
    oxysterol binding protein-like 9provided by RGD
    Primary source
    RGD:1311508
    See related
    EnsemblRapid:ENSRNOG00000033593 AllianceGenome:RGD:1311508
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable sterol binding activity. Predicted to be involved in lipid transport. Predicted to be located in intracellular membrane-bounded organelle. Predicted to be active in Golgi apparatus; cytosol; and membrane. Orthologous to human OSBPL9 (oxysterol binding protein like 9). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Adrenal (RPKM 372.3), Lung (RPKM 361.8) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Osbpl9 in Genome Data Viewer
    Location:
    5q34
    Exon count:
    29
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 5 NC_086023.1 (129047776..129190838, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 5 NC_051340.1 (123819106..123962213, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 5 NC_005104.4 (128694407..128839435, complement)

    Chromosome 5 - NC_086023.1Genomic Context describing neighboring genes Neighboring gene RNA, U6 small nuclear 304 Neighboring gene nardilysin convertase Neighboring gene microRNA 761 Neighboring gene uncharacterized LOC120103121 Neighboring gene uncharacterized LOC134486963 Neighboring gene uncharacterized LOC108351012 Neighboring gene calreticulin 4 Neighboring gene epidermal growth factor receptor pathway substrate 15

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC125192

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables sterol binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in lipid transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in Golgi apparatus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in Golgi apparatus ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in intracellular membrane-bounded organelle ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    oxysterol-binding protein-related protein 9

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001044234.2 → NP_001037699.2  oxysterol-binding protein-related protein 9

      See identical proteins and their annotated locations for NP_001037699.2

      Status: VALIDATED

      Source sequence(s)
      BC089838, BP491124, BP492064, CV110264
      UniProtKB/TrEMBL
      A0A8I5ZT38, A6JYX4
      Related
      ENSRNOP00000095283.1, ENSRNOT00000095896.2
      Conserved Domains (3) summary
      cd13290
      Location:5 → 106
      PH_ORP9; Human Oxysterol binding protein related protein 9 Pleckstrin homology (PH) domain
      pfam00169
      Location:6 → 98
      PH; PH domain
      pfam01237
      Location:364 → 710
      Oxysterol_BP; Oxysterol-binding protein

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086023.1 Reference GRCr8

      Range
      129047776..129190838 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039109563.2 → XP_038965491.1  oxysterol-binding protein-related protein 9 isoform X4

      UniProtKB/TrEMBL
      A0A8I5ZT38, A6JYX5, F1LRE5
      Related
      ENSRNOP00000063374.4, ENSRNOT00000065280.5
      Conserved Domains (2) summary
      cd13290
      Location:5 → 106
      PH_ORP9; Human Oxysterol binding protein related protein 9 Pleckstrin homology (PH) domain
      pfam01237
      Location:377 → 723
      Oxysterol_BP; Oxysterol-binding protein

    2. XM_039109562.2 → XP_038965490.1  oxysterol-binding protein-related protein 9 isoform X3

      UniProtKB/TrEMBL
      A0A8I5ZT38, A0A8I6A0M2
      Related
      ENSRNOP00000085644.1, ENSRNOT00000119557.2
      Conserved Domains (2) summary
      cd13290
      Location:5 → 106
      PH_ORP9; Human Oxysterol binding protein related protein 9 Pleckstrin homology (PH) domain
      pfam01237
      Location:387 → 733
      Oxysterol_BP; Oxysterol-binding protein

    3. XM_039109561.2 → XP_038965489.1  oxysterol-binding protein-related protein 9 isoform X2

      UniProtKB/TrEMBL
      A0A8I5ZT38, A0A8I6ANM6
      Related
      ENSRNOP00000094735.1, ENSRNOT00000108021.2
      Conserved Domains (2) summary
      cd13290
      Location:5 → 106
      PH_ORP9; Human Oxysterol binding protein related protein 9 Pleckstrin homology (PH) domain
      pfam01237
      Location:400 → 746
      Oxysterol_BP; Oxysterol-binding protein

    4. XM_039109559.2 → XP_038965487.2  oxysterol-binding protein-related protein 9 isoform X1

      UniProtKB/TrEMBL
      A0A0G2K9H3

    5. XM_039109568.2 → XP_038965496.1  oxysterol-binding protein-related protein 9 isoform X9

      UniProtKB/TrEMBL
      A0A8I6B608
      Conserved Domains (1) summary
      pfam01237
      Location:267 → 613
      Oxysterol_BP; Oxysterol-binding protein

    6. XM_039109566.2 → XP_038965494.1  oxysterol-binding protein-related protein 9 isoform X7

      UniProtKB/TrEMBL
      A0A8I6A1S0, A0A8I6B608
      Related
      ENSRNOP00000086199.1, ENSRNOT00000105729.2
      Conserved Domains (1) summary
      pfam01237
      Location:280 → 626
      Oxysterol_BP; Oxysterol-binding protein

    7. XM_063287388.1 → XP_063143458.1  oxysterol-binding protein-related protein 9 isoform X6

      UniProtKB/TrEMBL
      A0A8I6B608

    8. XM_039109564.2 → XP_038965492.1  oxysterol-binding protein-related protein 9 isoform X5

      UniProtKB/TrEMBL
      A0A8I6B608
      Conserved Domains (1) summary
      pfam01237
      Location:303 → 649
      Oxysterol_BP; Oxysterol-binding protein

    9. XM_039109569.2 → XP_038965497.1  oxysterol-binding protein-related protein 9 isoform X11

      UniProtKB/TrEMBL
      A0A8I6AVU6
      Conserved Domains (1) summary
      pfam01237
      Location:212 → 558
      Oxysterol_BP; Oxysterol-binding protein

    10. XM_063287389.1 → XP_063143459.1  oxysterol-binding protein-related protein 9 isoform X10

      UniProtKB/TrEMBL
      A0A8I6B608
      Related
      ENSRNOP00000097617.1, ENSRNOT00000118637.2

    11. XM_039109567.2 → XP_038965495.1  oxysterol-binding protein-related protein 9 isoform X8

      UniProtKB/TrEMBL
      A0A8I6B608
      Conserved Domains (1) summary
      pfam01237
      Location:275 → 621
      Oxysterol_BP; Oxysterol-binding protein

    12. XM_063287390.1 → XP_063143460.1  oxysterol-binding protein-related protein 9 isoform X1

      UniProtKB/TrEMBL
      A0A0G2K9H3
      Related
      ENSRNOP00000074997.2, ENSRNOT00000089441.3

    13. XM_063287391.1 → XP_063143461.1  oxysterol-binding protein-related protein 9 isoform X13

      UniProtKB/TrEMBL
      A6JYX6

    14. XM_039109571.2 → XP_038965499.1  oxysterol-binding protein-related protein 9 isoform X12

      Conserved Domains (1) summary
      pfam01237
      Location:68 → 414
      Oxysterol_BP; Oxysterol-binding protein
    Nucleotide Protein Strain
    Heading Accession and Version

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