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    Wdr20 WD repeat domain 20 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 314453, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Wdr20provided by RGD
    Official Full Name
    WD repeat domain 20provided by RGD
    Primary source
    RGD:1306499
    See related
    EnsemblRapid:ENSRNOG00000007333 AllianceGenome:RGD:1306499
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Wdr20a
    Summary
    Predicted to enable deubiquitinase activator activity. Predicted to be located in cytoplasm and nucleus. Orthologous to human WDR20 (WD repeat domain 20). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Thymus (RPKM 54.8), Kidney (RPKM 54.1) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Wdr20 in Genome Data Viewer
    Location:
    6q32
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 6 NC_086024.1 (135572502..135642688)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 6 NC_051341.1 (129751952..129821464)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 6 NC_005105.4 (135156984..135226425)

    Chromosome 6 - NC_086024.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC102549239 Neighboring gene heat shock protein 90 alpha family class A member 1 Neighboring gene ribosomal protein L35A like 2 Neighboring gene MOK protein kinase Neighboring gene uncharacterized LOC108351302 Neighboring gene transfer RNA isoleucine (anticodon AAU) 3

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables deubiquitinase activator activity ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    WD repeat-containing protein 20
    Names
    WD repeat domain 20a

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001100894.1 → NP_001094364.1  WD repeat-containing protein 20

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000006
      UniProtKB/TrEMBL
      A0A0G2K2B7, A6KBN0, D3ZVJ9
      Related
      ENSRNOP00000009709.5, ENSRNOT00000009709.9
      Conserved Domains (3) summary
      COG2319
      Location:147 → 435
      WD40; WD40 repeat [General function prediction only]
      sd00039
      Location:152 → 196
      7WD40; WD40 repeat [structural motif]
      cl02567
      Location:149 → 314
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086024.1 Reference GRCr8

      Range
      135572502..135642688
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039112414.2 → XP_038968342.1  WD repeat-containing protein 20 isoform X15

      UniProtKB/TrEMBL
      A0A8I6AK72

    2. XM_063262014.1 → XP_063118084.1  WD repeat-containing protein 20 isoform X1

      UniProtKB/TrEMBL
      A0A0G2K2B7, A6KBN0

    3. XM_017594187.3 → XP_017449676.1  WD repeat-containing protein 20 isoform X3

      UniProtKB/TrEMBL
      A0A0G2K2B7, A6KBN0
      Conserved Domains (2) summary
      sd00039
      Location:226 → 270
      7WD40; WD40 repeat [structural motif]
      cl29593
      Location:223 → 388
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

    4. XM_017594186.3 → XP_017449675.1  WD repeat-containing protein 20 isoform X3

      UniProtKB/TrEMBL
      A0A0G2K2B7, A6KBN0
      Conserved Domains (2) summary
      sd00039
      Location:226 → 270
      7WD40; WD40 repeat [structural motif]
      cl29593
      Location:223 → 388
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

    5. XM_039112410.2 → XP_038968338.1  WD repeat-containing protein 20 isoform X3

      UniProtKB/TrEMBL
      A0A0G2K2B7, A6KBN0
      Conserved Domains (2) summary
      sd00039
      Location:226 → 270
      7WD40; WD40 repeat [structural motif]
      cl29593
      Location:223 → 388
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

    6. XM_039112411.2 → XP_038968339.1  WD repeat-containing protein 20 isoform X5

      UniProtKB/TrEMBL
      A0A0G2K2B7, A6KBN0
      Related
      ENSRNOP00000087682.2, ENSRNOT00000114885.2
      Conserved Domains (2) summary
      sd00039
      Location:226 → 270
      7WD40; WD40 repeat [structural motif]
      cl29593
      Location:223 → 388
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

    7. XM_063262015.1 → XP_063118085.1  WD repeat-containing protein 20 isoform X2

      UniProtKB/TrEMBL
      A0A0G2K2B7, A6KBN0

    8. XM_017594188.3 → XP_017449677.1  WD repeat-containing protein 20 isoform X4

      UniProtKB/TrEMBL
      A0A0G2K2B7, A6KBN0

    9. XM_063262016.1 → XP_063118086.1  WD repeat-containing protein 20 isoform X6

      UniProtKB/TrEMBL
      A0A0G2K2B7, A6KBN0

    10. XM_063262021.1 → XP_063118091.1  WD repeat-containing protein 20 isoform X12

      UniProtKB/TrEMBL
      A0A8I6G8P3

    11. XM_063262017.1 → XP_063118087.1  WD repeat-containing protein 20 isoform X7

      UniProtKB/TrEMBL
      A0A0G2K2B7, A6KBN0

    12. XM_063262018.1 → XP_063118088.1  WD repeat-containing protein 20 isoform X8

      UniProtKB/TrEMBL
      A0A0G2K2B7, A6KBN0

    13. XM_063262020.1 → XP_063118090.1  WD repeat-containing protein 20 isoform X11

      UniProtKB/TrEMBL
      A0A0G2K2B7, A6KBN0

    14. XM_063262022.1 → XP_063118092.1  WD repeat-containing protein 20 isoform X14

      UniProtKB/TrEMBL
      A0A8I6G8P3

    15. XM_006240586.5 → XP_006240648.1  WD repeat-containing protein 20 isoform X13

      UniProtKB/TrEMBL
      A0A8I6G8P3
      Conserved Domains (3) summary
      COG2319
      Location:78 → 374
      WD40; WD40 repeat [General function prediction only]
      sd00039
      Location:91 → 135
      7WD40; WD40 repeat [structural motif]
      cl02567
      Location:88 → 253
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

    16. XM_063262019.1 → XP_063118089.1  WD repeat-containing protein 20 isoform X9

      UniProtKB/TrEMBL
      A0A0G2K2B7, A6KBN0

    17. XM_063262023.1 → XP_063118093.1  WD repeat-containing protein 20 isoform X17

      UniProtKB/TrEMBL
      A0A8I6A274

    18. XM_008764935.4 → XP_008763157.1  WD repeat-containing protein 20 isoform X16

      See identical proteins and their annotated locations for XP_008763157.1

      UniProtKB/TrEMBL
      A0A8I5ZK85, A0A8I6A274
      Related
      ENSRNOP00000083213.2, ENSRNOT00000118053.2

    19. XM_006240583.5 → XP_006240645.1  WD repeat-containing protein 20 isoform X10

      UniProtKB/TrEMBL
      A0A0G2K2B7, A0A8I6A891, A6KBN0
      Related
      ENSRNOP00000072178.3, ENSRNOT00000082595.3
      Conserved Domains (3) summary
      COG2319
      Location:147 → 435
      WD40; WD40 repeat [General function prediction only]
      sd00039
      Location:152 → 196
      7WD40; WD40 repeat [structural motif]
      cl02567
      Location:149 → 314
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

    20. XM_039112415.2 → XP_038968343.1  WD repeat-containing protein 20 isoform X18

      UniProtKB/TrEMBL
      A0A8I6A274

    RNA

    1. XR_005505530.2 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version

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