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    Krt79 keratin 79 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 683720, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Krt79provided by RGD
    Official Full Name
    keratin 79provided by RGD
    Primary source
    RGD:1583372
    See related
    EnsemblRapid:ENSRNOG00000058340 AllianceGenome:RGD:1583372
    Gene type
    protein coding
    RefSeq status
    INFERRED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable enzyme binding activity. Predicted to be a structural constituent of skin epidermis. Predicted to be involved in intermediate filament organization and keratinization. Predicted to be active in keratin filament. Orthologous to human KRT79 (keratin 79). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Liver (RPKM 49.2), Lung (RPKM 45.3) and 6 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Krt79 in Genome Data Viewer
    Location:
    7q36
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 7 NC_086025.1 (134935395..134946447, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 7 NC_051342.1 (133056710..133067750, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 7 NC_005106.4 (143528204..143538713, complement)

    Chromosome 7 - NC_086025.1Genomic Context describing neighboring genes Neighboring gene keratin 76 Neighboring gene keratin 4 Neighboring gene keratin 78 Neighboring gene cysteine-rich PDZ-binding protein pseudogene

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. A high-confidence interaction map identifies SIRT1 as a mediator of acetylation of USP22 and the SAGA coactivator complex. Armour SM, et al. Mol Cell Biol, 2013 Apr. PMID 23382074, Free PMC Article
    2. Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT). Gonzalez-Begne M, et al. J Proteome Res, 2009 Mar. PMID 19199708, Free PMC Article
    3. In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine. Principe S, et al. Proteomics, 2013 May. PMID 23533145, Free PMC Article
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables enzyme binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables structural constituent of skin epidermis IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in intermediate filament organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in keratinization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in keratin filament IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    keratin 79; keratin, type II cytoskeletal 79
    Names
    keratin 79, type II

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001432096.1 → NP_001419025.1  keratin 79

      Status: INFERRED

      Source sequence(s)
      JAXUCZ010000007
      UniProtKB/TrEMBL
      A0A8I5ZR22

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086025.1 Reference GRCr8

      Range
      134935395..134946447 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039080393.2 → XP_038936321.1  keratin, type II cytoskeletal 79 isoform X2

      UniProtKB/TrEMBL
      A0A0G2JW69, A6KCR9
      Conserved Domains (2) summary
      pfam00038
      Location:111 → 425
      Filament; Intermediate filament protein
      pfam16208
      Location:35 → 108
      Keratin_2_head; Keratin type II head

    2. XM_003750410.5 → XP_003750458.1  keratin, type II cytoskeletal 79 isoform X1

      Related
      ENSRNOP00000069765.2, ENSRNOT00000081518.3
      Conserved Domains (3) summary
      pfam00038
      Location:139 → 453
      Filament; Intermediate filament protein
      pfam10439
      Location:74 → 111
      Bacteriocin_IIc; Bacteriocin class II with double-glycine leader peptide
      pfam16208
      Location:28 → 136
      Keratin_2_head; Keratin type II head

    3. XM_039080394.2 → XP_038936322.1  keratin, type II cytoskeletal 79 isoform X3

      Conserved Domains (1) summary
      pfam00038
      Location:1 → 197
      Filament; Intermediate filament protein
    Nucleotide Protein Strain
    Heading Accession and Version

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