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    Irgq immunity-related GTPase Q [ Rattus norvegicus (Norway rat) ]

    Gene ID: 292708, updated on 9-Dec-2024

    Summary

    Official Symbol
    Irgqprovided by RGD
    Official Full Name
    immunity-related GTPase Qprovided by RGD
    Primary source
    RGD:1309409
    See related
    EnsemblRapid:ENSRNOG00000070901 AllianceGenome:RGD:1309409
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1309409
    Summary
    Predicted to enable GTP binding activity. Orthologous to human IRGQ (immunity related GTPase Q). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Brain (RPKM 91.9), Kidney (RPKM 59.4) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Irgq in Genome Data Viewer
    Location:
    1q21
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (89251846..89259799)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (80123925..80131881)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (81395922..81403872)

    Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene cell adhesion molecule 4 Neighboring gene zinc finger protein 428 Neighboring gene serine/arginine repetitive matrix 5 Neighboring gene phospholipase A2 inhibitor and Ly6/Plaur domain containing Neighboring gene X-ray repair cross complementing 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General protein information

    Preferred Names
    immunity-related GTPase family Q protein
    Names
    immunity-related GTPase family, Q

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001135742.4NP_001129214.3  immunity-related GTPase family Q protein

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000001
      UniProtKB/TrEMBL
      A0A8I5ZUT2
      Related
      ENSRNOP00000082584.1, ENSRNOT00000119508.2
      Conserved Domains (2) summary
      cd00267
      Location:362
      ABC_ATPase; ATP-binding cassette transporter nucleotide-binding domain
      cl38936
      Location:224286
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086019.1 Reference GRCr8

      Range
      89251846..89259799
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006228410.5XP_006228472.2  immunity-related GTPase family Q protein isoform X1

      Conserved Domains (2) summary
      cd00267
      Location:1372
      ABC_ATPase; ATP-binding cassette transporter nucleotide-binding domain
      pfam05049
      Location:204296
      IIGP; Interferon-inducible GTPase (IIGP)