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    NKP1 Nkp1p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 851991, updated on 9-Dec-2024

    Summary

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    Official Symbol
    NKP1
    Official Full Name
    Nkp1p
    Primary source
    SGD:S000002791
    Locus tag
    YDR383C
    See related
    AllianceGenome:SGD:S000002791; FungiDB:YDR383C; VEuPathDB:YDR383C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Predicted to be involved in cell division and meiotic cell cycle. Located in kinetochore. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See NKP1 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    1
    Sequence:
    Chromosome: IV; NC_001136.10 (1239960..1240676, complement)

    Chromosome IV - NC_001136.10Genomic Context describing neighboring genes Neighboring gene Coi1p Neighboring gene ribosomal protein P2B Neighboring gene putative ammonium permease ATO3 Neighboring gene elongation factor 2

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001136.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Recognition of centromere-specific histone Cse4 by the inner kinetochore Okp1-Ame1 complex. Deng S, et al. EMBO Rep, 2023 Dec 6. PMID 37983946, Free PMC Article
    2. Yeast Nkp2 is required for accurate chromosome segregation and interacts with several components of the central kinetochore. Tirupataiah S, et al. Mol Biol Rep, 2014 Feb. PMID 24385296
    3. The kinetochore prevents centromere-proximal crossover recombination during meiosis. Vincenten N, et al. Elife, 2015 Dec 14. PMID 26653857, Free PMC Article
    4. A TSC22-like motif defines a novel antiapoptotic protein family. Khoury CM, et al. FEMS Yeast Res, 2008 Jun. PMID 18355271, Free PMC Article
    5. The Structural Basis for Kinetochore Stabilization by Cnn1/CENP-T. Hinshaw SM, et al. Curr Biol, 2020 Sep 7. PMID 32679099

    See all (58) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    involved_in cell division IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in meiotic cell cycle IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in chromosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in chromosome, centromeric region IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in kinetochore IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in kinetochore IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Nkp1p
    NP_010671.4
    • Central kinetochore protein and subunit of the Ctf19 complex; mutants have elevated rates of chromosome loss; orthologous to fission yeast kinetochore protein fta4

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001136.10 Reference assembly

      Range
      1239960..1240676 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001180691.3 → NP_010671.4  TPA: Nkp1p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_010671.4

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VT17, Q12493
      UniProtKB/TrEMBL
      A6ZYY4, B3LFR7, C7GMF1, G2WBC3, N1P5F7
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q12493.2

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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