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    TAF7 TATA-binding protein-associated factor TAF7 [ Saccharomyces cerevisiae S288C ]

    Gene ID: 855267, updated on 9-Dec-2024

    Summary

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    Official Symbol
    TAF7
    Official Full Name
    TATA-binding protein-associated factor TAF7
    Primary source
    SGD:S000004840
    Locus tag
    YMR227C
    See related
    AllianceGenome:SGD:S000004840; FungiDB:YMR227C; VEuPathDB:YMR227C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    TAF67
    Summary
    Predicted to contribute to RNA polymerase II general transcription initiation factor activity. Involved in RNA polymerase II preinitiation complex assembly. Located in nucleus. Part of transcription factor TFIID complex. Used to study oligospermia. Orthologous to several human genes including TAF7 (TATA-box binding protein associated factor 7). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See TAF7 in Genome Data Viewer
    Location:
    chromosome: XIII
    Exon count:
    1
    Sequence:
    Chromosome: XIII; NC_001145.3 (722613..724385, complement)

    Chromosome XIII - NC_001145.3Genomic Context describing neighboring genes Neighboring gene mitochondrial 54S ribosomal protein YmL44 Neighboring gene oxidoreductase Neighboring gene RNA polymerase specificity factor Neighboring gene Rrp5p

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001145.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Taf2 mediates DNA binding of Taf14. Klein BJ, et al. Nat Commun, 2022 Jun 8. PMID 35676274, Free PMC Article
    2. The C Terminus of the RNA Polymerase II Transcription Factor IID (TFIID) Subunit Taf2 Mediates Stable Association of Subunit Taf14 into the Yeast TFIID Complex. Feigerle JT, et al. J Biol Chem, 2016 Oct 21. PMID 27587401, Free PMC Article
    3. Structural and functional insight into TAF1-TAF7, a subcomplex of transcription factor II D. Bhattacharya S, et al. Proc Natl Acad Sci U S A, 2014 Jun 24. PMID 24927529, Free PMC Article
    4. Bromodomain factor 1 corresponds to a missing piece of yeast TFIID. Matangkasombut O, et al. Genes Dev, 2000 Apr 15. PMID 10783167, Free PMC Article
    5. Bromodomain factor 1 (Bdf1) is phosphorylated by protein kinase CK2. Sawa C, et al. Mol Cell Biol, 2004 Jun. PMID 15143168, Free PMC Article

    See all (59) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    contributes_to RNA polymerase II general transcription initiation factor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    contributes_to RNA polymerase II general transcription initiation factor activity IC
    Inferred by Curator
    more info
    		  
    Process Evidence Code Pubs
    involved_in RNA polymerase II preinitiation complex assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in RNA polymerase II preinitiation complex assembly IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in transcription by RNA polymerase II IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in transcription initiation at RNA polymerase II promoter IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleus HDA PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of transcription factor TFIID complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of transcription factor TFIID complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of transcription factor TFIID complex IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    TATA-binding protein-associated factor TAF7
    NP_013954.1
    • TFIID subunit (67 kDa); involved in RNA polymerase II transcription initiation

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001145.3 Reference assembly

      Range
      722613..724385 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001182734.1 → NP_013954.1  TPA: TATA-binding protein-associated factor TAF7 [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_013954.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6W052, Q05021
      UniProtKB/TrEMBL
      B3LMB5, N1NZ16
      Conserved Domains (1) summary
      COG5414
      Location:1 → 498
      Taf7; TATA-binding protein-associated factor Taf7, part of the TFIID transcription initiation complex [Transcription]
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q05021.1

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