U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    NAN1 Nan1p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 855977, updated on 9-Dec-2024

    Summary

    Official Symbol
    NAN1
    Official Full Name
    Nan1p
    Primary source
    SGD:S000006047
    Locus tag
    YPL126W
    See related
    AllianceGenome:SGD:S000006047; FungiDB:YPL126W; VEuPathDB:YPL126W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    UTP17
    Summary
    Enables U3 snoRNA binding activity. Involved in maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) and positive regulation of transcription by RNA polymerase I. Located in nucleolus; peroxisome; and rDNA heterochromatin. Part of small-subunit processome and t-UTP complex. Used to study autism spectrum disorder; lissencephaly; and subcortical band heterotopia. Orthologous to human WDR75 (WD repeat domain 75). [provided by Alliance of Genome Resources, Dec 2024]
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See NAN1 in Genome Data Viewer
    Location:
    chromosome: XVI
    Exon count:
    1
    Sequence:
    Chromosome: XVI; NC_001148.4 (310210..312900)

    Chromosome XVI - NC_001148.4Genomic Context describing neighboring genes Neighboring gene Tbf1p Neighboring gene histone H1 Neighboring gene Kap120p Neighboring gene Spc29p

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables U3 snoRNA binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables mRNA binding HDA PubMed 
    Component Evidence Code Pubs
    part_of 90S preribosome HDA PubMed 
    is_active_in nucleolus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nucleolus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in nucleolus IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     
    located_in peroxisome IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in rDNA heterochromatin IDA
    Inferred from Direct Assay
    more info
    PubMed 
    part_of ribonucleoprotein complex IEA
    Inferred from Electronic Annotation
    more info
     
    part_of small-subunit processome IDA
    Inferred from Direct Assay
    more info
    PubMed 
    part_of small-subunit processome IEA
    Inferred from Electronic Annotation
    more info
     
    part_of t-UTP complex IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    Nan1p
    NP_015199.1
    • U3 snoRNP protein; component of the small (ribosomal) subunit (SSU) processosome containing U3 snoRNA; required for the biogenesis of18S rRNA; localizes to nucleolus and peroxisomes

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001148.4 Reference assembly

      Range
      310210..312900
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001183940.1NP_015199.1  TPA: Nan1p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_015199.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6W3P1, Q02931
      UniProtKB/TrEMBL
      B3LKU9, N1NW22
      Conserved Domains (2) summary
      sd00039
      Location:260295
      7WD40; WD40 repeat [structural motif]
      cl29593
      Location:258329
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...