MED1 Med1p [Saccharomyces cerevisiae S288C] - Gene

Summary

Official Symbol: MED1
Official Full Name: Med1p
Primary source: SGD:S000006274
Locus tag: YPR070W
See related: AllianceGenome:SGD:S000006274; FungiDB:YPR070W; VEuPathDB:YPR070W
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Saccharomyces cerevisiae S288C (strain: S288C)
Lineage: Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary: Predicted to enable transcription coregulator activity. Involved in negative regulation of transcription by RNA polymerase II and positive regulation of transcription by RNA polymerase II. Part of core mediator complex. [provided by Alliance of Genome Resources, Dec 2024]
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Chromosome XVI - NC_001148.4 Genomic Context describing neighboring genes

Go to nucleotide: Graphics FASTA GenBank

Growth-regulated co-occupancy of Mediator and Lsm3 at intronic ribosomal protein genes.
Title: Growth-regulated co-occupancy of Mediator and Lsm3 at intronic ribosomal protein genes.
MED1 is indepently recruited by the activator Met4.
Title: Independent recruitment of mediator and SAGA by the activator Met4.

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables molecular_function	ND No biological Data available more info
enables transcription coregulator activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in negative regulation of transcription by RNA polymerase II	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in positive regulation of transcription by RNA polymerase II	IEA Inferred from Electronic Annotation more info
involved_in positive regulation of transcription by RNA polymerase II	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in regulation of transcription by RNA polymerase II	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
part_of core mediator complex	IDA Inferred from Direct Assay more info	PubMed
part_of mediator complex	IEA Inferred from Electronic Annotation more info
located_in nucleus	IEA Inferred from Electronic Annotation more info

NP_015395.1

Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; essential for transcriptional regulation

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The following sections contain reference sequences that belong to a specific genome build. Explain