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    CG31673 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 35348, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG31673provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0051673
    Locus tag
    Dmel_CG31673
    See related
    AllianceGenome:FB:FBgn0051673
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BcDNA:LD14730; CCG31673; CG9332; Dmel\CG31673
    Summary
    Predicted to enable glyoxylate reductase (NADPH) activity and hydroxypyruvate reductase (NADH) activity. Predicted to be active in cytosol. Is expressed in organism. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG31673 in Genome Data Viewer
    Location:
    38F1-38F1; 2-54 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (20829609..20831161)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (20829609..20831161)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene Chemosensory protein B 38c Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Outer segment 5 Neighboring gene Serpin 38F

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Comparative transcriptomics across 14 Drosophila species reveals signatures of longevity. Ma S, et al. Aging Cell, 2018 Aug. PMID 29671950, Free PMC Article
    2. Following the 'tracks': Tramtrack69 regulates epithelial tube expansion in the Drosophila ovary through Paxillin, Dynamin, and the homeobox protein Mirror. Peters NC, et al. Dev Biol, 2013 Jun 15. PMID 23545328, Free PMC Article
    3. Transcription profiling in Drosophila eyes that overexpress the human glaucoma-associated trabecular meshwork-inducible glucocorticoid response protein/myocilin (TIGR/MYOC). Borrás T, et al. Genetics, 2003 Feb. PMID 12618402, Free PMC Article
    4. Candidate genes affecting Drosophila life span identified by integrating microarray gene expression analysis and QTL mapping. Lai CQ, et al. Mech Ageing Dev, 2007 Mar. PMID 17196240
    5. The composition and organization of Drosophila heterochromatin are heterogeneous and dynamic. Swenson JM, et al. Elife, 2016 Aug 11. PMID 27514026, Free PMC Article

    See all (30) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables NAD binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables glyoxylate reductase (NADH) activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables glyoxylate reductase (NADPH) activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables hydroxypyruvate reductase (NADH) activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in glyoxylate catabolic process ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in mitochondrion ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    located_in nucleus ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG31673-PA
    CG31673-PB
    NP_001286110.1
    NP_724294.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      20829609..20831161
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001299181.1 → NP_001286110.1  uncharacterized protein Dmel_CG31673, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001286110.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      X2J9A5
      Conserved Domains (2) summary
      COG1052
      Location:9 → 319
      LdhA; Lactate dehydrogenase or related 2-hydroxyacid dehydrogenase [Energy production and conversion, Coenzyme transport and metabolism, General function prediction only]
      cd05301
      Location:9 → 317
      GDH; D-glycerate dehydrogenase/hydroxypyruvate reductase (GDH)

    2. NM_165346.5 → NP_724294.1  uncharacterized protein Dmel_CG31673, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_724294.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VII9
      Related
      FBpp0080951
      Conserved Domains (2) summary
      COG1052
      Location:9 → 320
      LdhA; Lactate dehydrogenase or related 2-hydroxyacid dehydrogenase [Energy production and conversion, Coenzyme transport and metabolism, General function prediction only]
      cd05301
      Location:9 → 318
      GDH; D-glycerate dehydrogenase/hydroxypyruvate reductase (GDH)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VII9 Q9VII9
    X2J9A5 X2J9A5

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